补中益气汤治疗产后盆底功能障碍临床研究
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R711.5

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Clinical Study on Buzhong Yiqi Decoction for Postpartum Pelvic Floor Dysfunction
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    摘要:

    目的:观察补中益气汤治疗产后盆底功能障碍患者的临床效果及对尿动力学指标水平的影响。方 法:回顾性分析2021年10月—2023年10月磐安县妇幼保健院收治的84例产后盆底功能障碍患者的临床资料, 根据治疗方式的不同分为观察组与对照组各42例。对照组采用盆底肌锻炼干预治疗,观察组在对照组基础上 加用补中益气汤。2组均治疗8周。比较2组临床疗效,比较2组治疗前后尿动力学指标水平、盆底肌情况、阴 道壁基质金属蛋白酶-2(MMP-2) 及基质金属蛋白酶组织抑制因子-2(TIMP-2) 水平。结果:观察组总有效 率为95.2% (40/42),高于对照组81.0% (34/42)(P<0.05)。治疗后,2 组阴道收缩持续时间均延长(P< 0.05),阴道动态压力值及阴道收缩肌电值均增加(P<0.05),且观察组阴道收缩持续时间长于对照组(P< 0.05),阴道动态压力值及阴道收缩肌电值高于对照组(P<0.05)。治疗后,2组盆底功能障碍影响简易问 卷(PFIQ-7)、盆底功能障碍问卷(PFDI-20) 评分均降低(P<0.05),且观察组低于对照组(P<0.05);2组 盆底器官脱重/尿失禁及性功能调查问卷-12 (PISQ-12) 评分均升高(P<0.05),且观察组高于对照组(P< 0.05)。治疗后,2组最大膀胱容量、最大尿流量均升高,且观察组高于对照组(P<0.05)。治疗后,2组阴道 壁MMP-2水平降低(P<0.05),且观察组低于对照组(P<0.05);2组TIMP-2水平升高(P<0.05),且观察 组高于对照组(P<0.05)。结论:补中益气汤可提高产后盆底功能障碍患者的临床疗效,改善盆底肌情况,提 高尿动力学指标水平及患者的生活质量。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Buzhong Yiqi Decoction on patients with postpartum pelvic floor dysfunction and its effect on urodynamic parameters. Methods: A retrospective analysis was conducted on the clinical data of 84 patients admitted to the Pan'an County Maternal and Child Health Hospital from October 2021 to October 2023 with postpartum pelvic floor dysfunction. The patients were divided into the observation group and the control group based on different treatment methods, with 42 cases in each group. The control group was treated with pelvic floor muscle exercise intervention, and the observation group was additionally treated with Buzhong Yiqi Decoction based on the treatment of the control group. Both groups were treated for eight weeks. Clinical effects, urodynamic parameters,pelvic floor muscle condition,and levels of vaginal wall matrix metalloproteinase-2( MMP-2) and tissue inhibitor of metalloproteinases-2 (TIMP-2) in the two groups were compared before and after treatment. Results: The total effective rate in the observation group was 95.2%(40/42), higher than 81.0% (34/42) in the control group (P<0.05). After treatment, both groups showed prolonged vaginal contraction duration (P<0.05), increased vaginal dynamic pressure values,and increased vaginal contraction electromyography values (P<0.05). The observation group had longer vaginal contraction duration,higher vaginal dynamic pressure value,and higher vaginal contraction electromyography value compared to the control group (P<0.05). After treatment,both groups had reduced scores of Pelvic Floor Impairment Questionnaire-7(PFIQ-7) and Pelvic Floor Distress Inventory-Short Form 20( PFDI- 20)( P<0.05),with the observation group scoring lower than the control group( P<0.05);both groups had increased Pelvic Floor Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire-12(PISQ-12) scores (P<0.05), with the observation group scoring higher than the control group (P<0.05). After treatment,maximum bladder capacity and maximum urine flow rate were increased in the two groups,with the observation group showing higher values than the control group (P<0.05). After treatment,MMP-2 levels in the vaginal wall were decreased in the two groups (P< 0.05), with the observation group showing lower level than the control group (P<0.05); TIMP-2 levels were increased in the two groups( P<0.05),with the observation group showing higher level than the control group( P<0.05). Conclusion: Buzhong Yiqi Decoction can enhance the clinical effect on patients with postpartum pelvic floor dysfunction,improve pelvic floor muscle condition,elevate urodynamic parameters,and improve patients' quality of life.

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孔文娟,施锡亮,陈岚岚.补中益气汤治疗产后盆底功能障碍临床研究[J].新中医,2025,57(7):61-65

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  • 在线发布日期: 2025-04-09
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