Abstract:Objective:To observe the clinical effect of modified Fangfeng Tongsheng Powder in the treatment of functional constipation of patients with elderly hypertension. Methods:A total of 76 elderly patients with hypertension and functional constipation admitted to Lishui Hospital of Traditional Chinese Medicine from January 2021 to December 2022 were selected and divided into an observation group and a control group,with 38 cases in each group, according to the random number table method. The control group received conventional treatment,and the observation group was treated with the modified Fangfeng Tongsheng Powder in addition to the treatment in the control group. Both groups were treated for four weeks. The clinical effects and the incidence of adverse reactions were compared between the two groups. The levels of serum motilin (MTL) and vasoactive intestinal peptide (VIP),the 72-hour marker expulsion rate, and the scores of Constipation Severity Score (CSS) and the Patient Assessment of Constipation Quality of Life (PAC-QOL) were compared before and after treatment in both groups. Results:The total effective rate of western medical treatment in the observation group was 89.47% (34/38),which was higher than that of 68.42% (26/38) in the control group( P<0.05). The total effective rate of Chinese medical treatment in the observation group was 92.11%( 35/ 38), which was higher than that of 71.05% (27/38) in the control group (P<0.05). After treatment, the levels of serum MTL and VIP in both groups were increased (P<0.05),and the levels in the observation group were higher than those in the control group (P<0.05). After treatment, the 72-hour marker expulsion rates in both groups were increased (P<0.05),and the rate in the observation group was higher than that in the control group (P<0.05);the CSS and PAC-QOL scores in both groups were decreased (P<0.05),and the observation group had lower scores than the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The modified Fangfeng Tongsheng Powder has a significant therapeutic effect on functional constipation of patients with elderly hypertension and helps to improve the symptoms and quality of life of patients.