导痰汤加减联合八卦阵针刺疗法治疗痰湿内盛型腹型肥胖临床研究
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R259

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吴阶平医学基金会临床科研专项(320.6750.2021-06-28)


Clinical Study on Modified Daotan Decoction Combined with Bagua Acupuncture Therapy for Abdominal Obesity of Internal Retention of Phlegm-Damp Type
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    摘要:

    目的:观察导痰汤加减联合八卦阵针刺疗法治疗痰湿内盛型腹型肥胖的临床疗效。方法:选择 2021年8月—2023年8月舟山市中医院治疗的92例痰湿内盛型腹型肥胖患者,按随机数字表法分为对照组和研 究组各46例。2组均给予基础治疗,对照组加用八卦阵针刺疗法治疗,研究组在对照组基础上给予导痰汤加减 治疗。比较2组临床疗效,体质量、体质量指数(BMI)、肝脏脂肪含量、胃肠动力学指标[餐后胃电图幅值、 胃运动节律慢波比、胃窦收缩频率]、胰岛素抵抗指数(HOMA-IR)、瘦素、脂联素、超敏C-反应蛋白(hs-CRP)、 内脂素、总抗氧化能力(T-AOC) 水平。结果:治疗后,研究组总有效率为97.78% (44/45),高于对照组 81.82%(36/44)(P<0.05);2组肝脏脂肪含量、体质量及BMI均降低(P<0.05),且研究组低于对照组(P< 0.05);2 组餐后胃电图幅值、胃运动节律慢波比、胃窦收缩频率均升高(P<0.05),且研究组高于对照 组(P<0.05);2组HOMA-IR、内脂素、瘦素水平均降低(P<0.05),且研究组低于对照组(P<0.05);2组 脂联素水平均升高(P<0.05),且研究组高于对照组(P<0.05);2组hs-CRP水平均降低(P<0.05),且研究 组低于对照组(P<0.05);2组T-AOC水平均升高(P<0.05),且研究组高于对照组(P<0.05)。结论:导痰 汤加减联合八卦阵针刺疗法治疗痰湿内盛型腹型肥胖,可改善脂肪细胞因子水平,抑制炎症及氧化应激反应, 降低肝脏脂肪含量,改善胰岛素抵抗及胃肠动力,减轻体质量,降低BMI,提升临床疗效。

    Abstract:

    Abstract: Objective: To investigate the clinical effects of modified Daotan Decoction combined with Bagua acupuncture therapy in treating abdominal obesity of the internal retention of phlegm-damp type. Methods:A total of 92 patients with abdominal obesity of internal retention of phlegm-damp type treated at Zhoushan Hospital of Traditional Chinese Medicine from August 2021 to August 2023 were selected and randomly divided into a control group and a study group,each with 46 cases. Both groups received basic treatment. The control group was additionally treated with Bagua acupuncture therapy, while the study group was additionally treated with modified Daotan Decoction based on the control group's treatment. Clinical effects,body weight,body mass index (BMI),liver fat content,gastrointestinal motility indices (postprandial electrogastrogram amplitude, the slow wave ratio of gastric motility rhythm, and antral contraction frequency),insulin resistance index (HOMA-IR), and levels of leptin, adiponectin, high-sensitivity C-reactive protein (hs-CRP), visfatin, and total antioxidant capacity (T-AOC) were compared between the two groups. Results:After treament,the total effective rate in the study group was 97.78% (44/45),higher than that of 81.82% (36/44) in the control group (P<0.05). The liver fat content,body weight,and BMI in the two groups were lower compared with those before treatment (P<0.05), and the study group were lower than the control group (P< 0.05). The postprandial electrogastrogram amplitude, the slow wave ratio of gastric motility rhythm, and antral contraction frequency in the two groups were higher compared with those before treatment (P<0.05), and the study group were higher than the control group (P<0.05). The levels of HOMA-IR,visfatin,and leptin in the two groups were lower compared with those before treatment (P<0.05), and the study group were lower than the control group (P<0.05), while the level of adiponectin in the two groups were higher compared with those before treatment (P<0.05),and the study group was higher than the control goup (P<0.05). The hs-CRP content in the two groups were lower compared with those before treatment (P<0.05), and the study group was lower than the control group (P<0.05),the T-AOC content in the two groups were higher compared with those before treatment (P<0.05), and the study group was higher than the control goup(P<0.05). Conclusion: Modified Daotan Decoction combined with Bagua acupuncture therapy can improve the levels of adipocytokines, inhibit inflammation and oxidative stress, reduce liver fat content, improve insulin resistance, enhance gastrointestinal motility, bring down body weight and BMI,and enhance clinical efficacy in patients with abdominal obesity of internal retention of phlegm-damp type.

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胡蕾,王力,胡俊华.导痰汤加减联合八卦阵针刺疗法治疗痰湿内盛型腹型肥胖临床研究[J].新中医,2025,57(7):71-76

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  • 在线发布日期: 2025-04-09
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