Abstract： Hashimoto's thyroiditis is a chronic， autoimmune， non-infectious inflammatory disease that targets the thyroid gland as an antigen. The body-qi-spirit is closely related to the etiology and pathogenesis of Hashimoto's thyroiditis. Emotional factors are key pathogenic factors in Hashimoto's thyroiditis，liver constraint and qi stagnation is the fundamental cause of the disease， and the binding of qi， blood， and phlegm is a critical factor in disease progression， ultimately leading to morphological changes in the thyroid such as size and texture. The treatment of Hashimoto's thyroiditis should focus on regulating qi，calming the mind，and treating the body. Regulating qi should emphasize the liver's function of governing the free flow of qi；calming the mind should focus on the nourishment of the heart and liver；treating the body requires both internal and external therapies to remove blood stasis，dissolve phlegm， and disperse goiter. This article explores the connection between the trinity of body-qi-spirit and Hashimoto's thyroiditis and its clinical diagnosis and treatment，aiming to provide new insights for clinical practice.