Abstract: The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is the dysfunction of triple energizers and abnormal water transportation and transformation, which is related to the dysfunction of the spleen, lung and kidney. Modified Wuling Powder can be used to warm yang and transform qi and promote urination and percolate dampness for unblocked dynamics of triple energizers and regulation of internal organs. When upper energizer disorders predominate, it should mainly diffuse the lung to resolve dampness; for middle energizer disorders, it should mainly supplement deficiency and regulate the middle energizer; for lower energizer disorders, it should mainly warm the kidney to transform qi.