Abstract: Objective: To explore the medication rules of Chinese herbal compound patents for the treatment of chronic pharyngitis (CP). Methods: The prescription data for CP treatment in the national patent database were recorded,and Excel 2021 was used to count the frequency of herbal use and their natures,flavors and channel entries. R 4.3.3 software was adopted for association rule, clustering, and correlation coefficient analysis. Cytoscape 3.8 was used to construct a core complex network of Chinese herbs and extract dense Chinese herbal clusters. Results:A total of 457 Chinese herbal compound patents were included, involving 1 014 herbs. The high-frequency herbs included Glycyrrhizae Radix et Rhizoma, Platycodonis Radix, Ophiopogonis Radix, Lonicerae Japonicae Flos, and Scrophulariae Radix. The commonly used herbal pairs included Platycodoni Radix-Glycyrrhizae Radix et Rhizoma, Ophiopogonis Radix-Glycyrrhizae Radix et Rhizoma, Lonicerae Japonicae Flos-Glycyrrhizae Radix et Rhizoma, etc. The commonly used triplet herb combinations included Ophiopogonis Radix-Platycodoni Radix-Glycyrrhizae Radix et Rhizoma, Scrophulariae Radix-Ophiopogonis Radix-Glycyrrhizae Radix et Rhizoma, Lonicerae Japonicae Flos- Platycodoni Radix-Glycyrrhizae Radix et Rhizoma,etc. Four groups of core herbal combinations were extracted through clustering analysis,and one potential herbal combination was identified. Conclusion:The basic formula for Chinese herbal compound patents in the treatment of CP is to clear heat,resolve toxins,and soothe the throat,and herbs that nourish yin, resolve phlegm, eliminate dampness, invigorate blood and remove stasis can be added according to syndrome differentiation. This provides a reference for clinical medication and development of new drug.