基于数据挖掘分析梁傍顺治疗肺结核用药规律
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R521

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广东省中医药局科研项目(20231269);广州市三级名中医传承项目梁傍顺工作室项目


Analysis on Medication Rules of LIANG Bangshun in Treating Tuberculosis Based on Data Mining
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    摘要:

    目的:基于数据挖掘分析梁傍顺教授运用中医药治疗肺结核的用药规律。方法:收集2021年5月 1日—2024年4月30日在广州市胸科医院中医科病房及门诊诊治的肺结核患者的临床资料。将所得资料信息录 入Microsoft Excel建立数据库,进行药物用药、性味归经频次分析。运用SPSS Modeler软件、R语言等对数据进 行关联规则、聚类及相关性分析。结果:共纳入符合标准的中药处方259份,涉及中药149味,总用药频次 3 417次。使用频次最高的药物为甘草,其次为茯苓、党参、麸炒白术、炒薏苡仁等;药物四气以温、凉、平 居多,五味以甘、苦、辛多见,归经以肺经、脾经为主,关联规则支持度最高的为麸炒白术-甘草,其次为党 参-甘草,共现次数最高的是茯苓-麸炒白术,经聚类分析获得3类中药核心组合,3组药物的相关性较高。结 论:梁傍顺教授治疗肺结核,注重培土调中枢、培土生金,共同调理肺脾两脏功能。

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    Abstract:Objective:To analyze the medication rules of Professor LIANG Bangshun in treating tuberculosis with Chinese medicine based on data mining. Methods:The clinical data of patients with tuberculosis diagnosed and treated in the Chinese medicine ward and outpatient department of Guangzhou Chest Hospital from May 1,2021 to April 30, 2024 were collected and input into Microsoft Excel to establish a database for frequency analysis of medications, properties,flavors and meridian entries of Chinese herbs. SPSS Modeler software and R language were used to analyze the association rules,clustering and correlation of the data. Results:A total of 259 prescriptions of Chinese medicine were included,involving 149 Chinese herbs,with a total frequency of 3 417 times. The most frequently used Chinese herbs were Glycyrrhizae Radix et Rhizoma, followed by Poria, Codonopsis Radix, Atractylodis Macrocephalae Rhizoma stir-fried with bran, fried Coicis Semen, etc. The four properties of the Chinese herbs were mostly warm, cool and neutral,the five flavors were mostly sweet,bitter and pungent,and the meridian entries were mainly the lung and spleen. The association rules analysis showed that Atractylodis Macrocephalae Rhizoma stir-fried with bran- Glycyrrhizae Radix et Rhizoma was with the highest support, followed by Codonopsis Radix-Glycyrrhizae Radix et Rhizoma, and Poria-Atractylodis Macrocephalae Rhizoma stir-fried with bran was with the highest number of cooccurrences. Three core combinations of Chinese herbs were obtained by clustering analysis, and the correlation between the three groups of Chinese herbs was higher. Conclusion:In the treatment of tuberculosis,Professor LIANG Bangshun pays more attention to bank up the earth for central regulation and metal generation, jointly regulating the lung function and spleen function.

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黄晋,潘静洁,刘堂营,指导:梁傍顺.基于数据挖掘分析梁傍顺治疗肺结核用药规律[J].新中医,2025,57(8):6-11

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  • 在线发布日期: 2025-04-27
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