Abstract： Objective： To observe the clinical effect of the combination use of modified Wuren Decoction and thumb-tack needle therapy on constipation of qi stagnation and blood stasis type after surgery of hemorrhoids. Methods： A total of 80 patients with constipation of qi stagnation and blood stasis type after surgery of hemorrhoid were selected from Nanyang First People's Hospital from April 2022 to April 2024 and randomly divided into the observation group and the control group by computer， with 40 cases in each group. The control group was treated with thumb-tack needle therapy， and the observation group was treated with modified Wuren Decoction combined with thumb-tack needle therapy. With seven days as a course of treatment， both groups were treated for two courses. The clinical effects and safety in the two groups were evaluated. The traditional Chinese medicine（TCM） syndrome scores， pro-inflammatory factors [interleukin（ IL）-6，IL-8，IL-17 and IL-1]，neurotransmitters [neuropeptide Y（ NPY），vasoactive intestinal peptide （VIP）， 5-hydroxytryptamine （5-HT） and substance P （SP）] and anorectal dynamics indexes （rectal resting pressure， anorectal maximum systolic pressure and anal resting pressure ） were compared before and after treatment between the two groups. Results：After treatment，the total effective rate was 92.50%（37/40） in the observation group， higher than that of 72.50%（29/40） in the control group，the difference being significant （P＜0.05）. The scores of dry stools， desire for defecation but with constipation， incomplete defecation， abdominal distension and pain， and stuffiness-fullness in the chest and hypochondrium in the two groups were reduced when compared with those before treatment. The scores of the above five scores in the observation group were lower than those in the control group， differences being significant （P＜0.05）. The levels of IL-6，IL-8，IL-17，IL-1，NPY，VIP and 5-HT in the two groups were down-regulated when compared with those before treatment，and the above seven levels in the observation group were lower than those in the control group， differences being significant （P＜0.05）. The SP levels in the two groups were elevated when compared with those before treatment，and the SP level in the observation group was higher than that in the control group， the differences being significant （P＜0.05）. The rectal resting pressure， anorectal maximum systolic pressure and anal resting pressure in the two groups were dwindled when compared with those before treatment， and the rectal resting pressure， anorectal maximum systolic pressure and anal resting pressure in the observation group were smaller than those in the control group，differences being significant （P＜0.05）. Conclusion： The combination use of modified Wuren Decoction and thumb-tack needle therapy has a definite curative effect on constipation of qi stagnation and blood stasis type after surgery of hemorrhoids，which can relieve the clinical symptoms， regulate the levels of pro-inflammatory factors and neurotransmitters，and improve the anorectal dynamics.