基于红外热成像技术的温肾运脾扶阳法治疗“长新冠”相关性慢性咳嗽临床研究
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R256.11

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浙江省中医药科研项目(2024ZL1278)


Clinical Study on Wenshen Yunpi Fuyang Method Based on Infrared Thermal Imaging Technology for "Long COVID"-Related Chronic Cough
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    摘要:

    目的:探讨温肾运脾扶阳法对“长新冠”相关性慢性咳嗽的治疗效果及其与红外热成像图谱的关 系。方法:选取于2022年6月—2024年1月在丽水市中医院治疗的“长新冠”相关性慢性咳嗽120例,按照随 机数字表法分为常规治疗组、中药组及中西医结合组,每组40例。常规治疗组给予西药治疗,中药组给予温 肾运脾扶阳中药治疗,中西医结合组给予西药联合温肾运脾扶阳中药治疗。治疗前后分别采用非制冷氧化钒焦 平面阵列红外热成像技术对脾胃区和肾区进行扫描,记录探点温度和平均温度,同时评估咳嗽症状、咳嗽特异 性生活量表(CQLQ) 评分。结果: 治疗后, 中西医结合组治愈率、总有效率分别为40.00% (16/40)、 90.00% (36/40), 均分别高于中药组的20.00% (8/40)、80.00% (32/40) 和常规治疗组的5.00% (2/40)、 60.00%(24/40),组间两两比较,差异均有统计学意义(P<0.05);中药组治愈率、总有效率均高于常规治疗 组(P<0.05)。治疗后,3组每天咳嗽频率、咳嗽强度评分均较治疗前减少(P<0.05);中西医结合组每天咳 嗽频率、咳嗽强度评分均少于中药组、常规治疗组(P<0.05),中药组每天咳嗽频率、咳嗽强度评分均少于常 规治疗组(P<0.05)。治疗后,3组CQLQ评分较治疗前降低(P<0.05);中西医结合组CQLQ评分低于中药 组、常规治疗组(P<0.05);中药组CQLQ评分均低于常规治疗组(P<0.05)。治疗后,3组脾胃区探点温度 和平均温度、肾区探点温度和平均温度均较治疗前升高(P<0.05);中西医结合组2个区探点温度和平均温度 均高于中药组、常规治疗组(P<0.05);中药组2个区探点温度和平均温度均高于常规治疗组(P<0.05)。治 疗期间,3组不良反应率比较,差异无统计学意义(P>0.05)。结论:温肾运脾扶阳法能够有效改善“长新冠” 相关性慢性咳嗽患者的临床症状和生活质量,提高其脾胃和肾的温度,调节患者体质,其作用机制可能与改善 脾胃区、肾区红外热成像图谱有关。

    Abstract:

    Abstract:Objective:To investigate the therapeutic effects of Wenshen Yunpi Fuyang method on "Long COVID" -related chronic cough and its relationship with infrared thermal imaging patterns. Methods: A total of 120 cases of patients with "Long COVID"-related chronic cough who were treated at Lishui Hospital of Traditional Chinese Medicine from June 2022 to January 2024 were selected and divided into three groups according to the random number table method:the routine treatment group,the Chinese medicine group,and the integrated Chinese and western medicine group, with 40 cases in each group. The routine treatment group received western medicine; the Chinese medicine group received Wenshen Yunpi Fuyang herbal treatment, and the integrated Chinese and western medicine group received a combination of western medicine and Chinese herbal treatment. Before and after treatment,non-refrigerated vanadium oxide focal plane array infrared thermal imaging technology was used to scan the spleen-stomach area and kidney area;the probe temperature and average temperature were recorded;the scores of cough symptoms,Coughspecific Quality of Life Questionnaire (CQLQ) were assessed. Results: After treatment, the cure rate and total effective rate in the integrated Chinese and western medicine group were 40.00% (16/40) and 90.00% (36/40), respectively,which were higher than those in the Chinese medicine group 20.00% (8/40),80.00% (32/40) and the routine treatment group 5.00% (2/40),60.00% (24/40),with significant differences between groups (P<0.05);the cure rate and total effective rate in the Chinese medicine group were also higher than those in the routine treatment group (P<0.05). After treatment,daily cough frequency and cough intensity scores in the three groups were decreased when compared with those before treatment (P<0.05);the integrated Chinese and western medicine group had lower daily cough frequency and cough intensity score than the Chinese medicine group and the routine treatment group (P< 0.05), and the Chinese medicine group had lower daily cough frequency and cough intensity score than the routine treatment group (P<0.05). After treatment, CQLQ scores in the three groups were decreased when compared with those before treatment (P<0.05);the integrated Chinese and western medicine group had lower CQLQ score than the Chinese medicine group and the routine treatment group (P<0.05),and the Chinese medicine group had lower score than the routine treatment group (P<0.05). After treatment,probe temperature and average temperature in the spleenstomach area and kidney area in the three groups were increased when compared with those before treatment (P<0.05); the integrated Chinese and western medicine group had higher probe temperature and average temperature in both areas than the Chinese medicine group and the routine treatment group (P<0.05), and the Chinese medicine group had higher probe temperature and average temperature than the routine treatment group (P<0.05). During the treatment period, there was no significant difference in the incidence of adverse reactions among the groups (P>0.05). Conclusion: The Wenshen Yunpi Fuyang method can effectively improve clinical symptoms and quality of life in patients with "Long COVID"-related chronic cough,increase the temperature of the spleen-stomach and kidney areas, and regulate the patient's constitution. Its mechanism of action can be related to changes in infrared thermal imaging patterns in spleen-stomach region and kidney region.

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徐夏薇,倪京丽,陈海涛,缪克雷.基于红外热成像技术的温肾运脾扶阳法治疗“长新冠”相关性慢性咳嗽临床研究[J].新中医,2025,57(8):54-59

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  • 在线发布日期: 2025-04-27
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