Abstract：Objective：To observe the clinical effect of external application with Rhei Radix et Rhizoma and Natrii Sulfas Exsiccatus on abdominal incision healing after cesarean section. Methods：A total of 96 parturients undergoing cesarean section were selected as the study subjects and divided into the control group and the observation group according to the random number table method，with 48 cases in each group. The control group was treated with routine dressing change after surgery， and the observation group was treated with external application with Rhei Radix et Rhizoma and Natrii Sulfas Exsiccatus based on the treatment of the control group. The clinical effects， occlusion of wounds， improvement of incision （regression time of induration， and redness and swelling） and adverse reactions， and the scores of Visual Analogue Scale（ VAS） of pain and Vancouver Scar Scale（ VSS） of surface of wounds before and after treatment were compared between the two groups. Results：After treatment，the total clinical effective rate was 93.75% （45/48） in the observation group， higher than that of 77.08% （37/48） in the control group （P＜0.05）. The excellent rate of occlusion of wounds was 72.92%（ 35/48） in the observation group，higher than that of 52.08%（ 25/48） in the control group（ P＜0.05）. The occlusion rate of wounds in the observation group was higher than that in the control group，and the regression time of induration and redness was shorter than that in the control group （P＜0.05）. Five， seven and ten days after surgery， the VAS scores in the observation group were lower than those in the control group respectively（ P＜0.05）；ten days and one month after surgery，the VSS score in the observation group was respectively lower than that in the control group （P＜0.05）. The incidence of adverse reactions such as fat liquefaction， cracking incision， hematoma and infection in the observation group was lower than that in the control group （P＜0.05）. Conclusion： The external application of Rhei Radix et Rhizoma and Natrii Sulfas Exsiccatus has a definite curative effect on abdominal incision healing after cesarean section， which can effectively promote the disappearance of induration and redness，relieve the pain，help occlusion of incision，improve the scars on the surface of wound and the incidence of adverse reactions.