热补针法针刺蝶腭神经节联合氯雷他定治疗肺气虚寒型变应性鼻炎临床研究
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R765.21;R245.3

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Clinical Study on Warm Reinforcement Acupuncture at Sphenopalatine Ganglion Combined with Loratadine in Treating Allergic Rhinitis of Deficiency-Cold of the Lung Qi Type
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    摘要:

    目的:观察热补针法针刺蝶腭神经节联合氯雷他定治疗肺气虚寒型变应性鼻炎(AR) 的临床疗 效。方法:选取2022年10月—2024年3月在丽水市中心医院耳鼻咽喉科治疗的92例肺气虚寒型AR患者,按 随机数字表法分为治疗组与对照组各46例,2组各44例完成研究。2组均给予氯雷他定片治疗,在此基础上, 治疗组采用热补针法针刺蝶腭神经节治疗,对照组采用传统针法针刺蝶腭神经节治疗,2组均治疗4周。比 较2组临床疗效及不良反应发生率,比较2组治疗前后鼻症状[鼻症状总评分表(TNSS)]、免疫指标[血清 免疫球蛋白E (IgE)、白细胞介素-4 (IL-4)、干扰素-γ (IFN-γ)]、生活质量[鼻结膜炎生存质量量 表(RQLQ)] 的变化。结果:治疗组临床疗效总有效率93.18% (41/44),高于对照组75.00% (33/44)(P< 0.05)。治疗4周后,2组TNSS量表、RQLQ量表中各项评分及总分均较治疗前降低(P<0.05),治疗组TNSS 量表、RQLQ量表中各项评分及总分均低于对照组(P<0.05)。2组血清IgE、IL-4水平均较治疗前降低(P< 0.05),治疗组血清IgE、IL-4水平均低于对照组(P<0.05);2组血清IFN-γ水平均较治疗前升高(P<0.05), 治疗组血清IFN-γ水平高于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结 论:热补针法针刺蝶腭神经节联合氯雷他定治疗肺气虚寒型AR疗效显著,可缓解鼻部症状、调节机体免疫 力、减轻炎症反应及提高生活质量,安全性高。

    Abstract:

    Abstract:Objective:To observe the clinical efficacy of warm reinforcement acupuncture at the sphenopalatine ganglion combined with Loratadine in treating allergic rhinitis (AR) of deficiency-cold of the lung qi type. Methods:A total of 92 AR patients of deficiency-cold of the lung qi type treated at the Department of Otolaryngology,Lishui Central Hospital from October 2022 to March 2024 were selected and randomly divided into the treatment group and the control group by random number table method,with 46 cases in each group. There were 44 cases in each group completing the study. Both groups received Loratadine Tablets, while the treatment group additionally received warm reinforcement acupuncture at the sphenopalatine ganglion, and the control group received traditional acupuncture at the sphenopalatine ganglion. Both groups were treated for four weeks. The clinical efficacy and incidence of adverse reactions were compared between the two groups. Changes in nasal symptoms [Total Nasal Symptom Score (TNSS)], immune indicators [serum immunoglobulin E (IgE), interleukin-4 (IL-4), and interferon-γ (IFN-γ)], and quality of life [Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ)] of the two grups were compared before and after treatment. Results: The total effective rate was 93.18% (41/44) in the treatment group, significantly higher than that of 75.00% (33/44) in the control group (P<0.05). After four weeks of treatment,the sub-item scores and total scores of the TNSS and RQLQ scales were decreased in both groups when compared with those before treatment (P<0.05),with the treatment group showing lower scores than the control group (P<0.05). Serum IgE and IL-4 levels were decreased in both groups when compared with those before treatment (P<0.05),with the treatment group showing lower levels than the control group (P<0.05). Serum IFN-γ levels were increased in both groups when compared with those before treatment (P<0.05),with the treatment group showing higher levels than the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Warm reinforcement acupuncture at the sphenopalatine ganglion combined with Loratadine is effective in treating AR of deficiency-cold of the lung qi type. It can alleviate nasal symptoms,regulate immune function,reduce inflammatory responses,improve quality of life,and demonstrate high safety.

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黄春唯,陈婷婷,徐红伟.热补针法针刺蝶腭神经节联合氯雷他定治疗肺气虚寒型变应性鼻炎临床研究[J].新中医,2025,57(9):114-119

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  • 在线发布日期: 2025-05-12
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