Abstract： Objective： To analyze the potential mechanism of action of Danlong Oral Liquid in the treatment of bronchial asthma via network pharmacology methods and verify the results via molecular docking technique. Methods： Effective components and their targets in Danlong Oral Liquid were retrieved from the TCSMP，Chemical Professional Database， PubChem， SwissADME， and SwissTargetPrediction databases. The Cytoscape software was used to construct a "Chinese herbal medicine-effective component-target" network diagram to screen out the main effective components. Disease targets for asthma were obtained from the GeneCards and OMIM databases. Intersection targets between the medicine and the disease were further extracted， and a protein-protein interaction （PPI） network was constructed via the String database to screen out core targets from the intersection targets. The DAVID database was used to perform Gene Ontology （GO） biological function analysis and Kyoto Encyclopedia of Genes and Genomes （KEGG） pathway enrichment analysis on the intersection targets. Finally，molecular docking of the main effective components of the medicine with the core targets was performed in AutoDock software. Results：A total of 238 effective components， 380 medicinal targets， and 1 183 asthma-related targets were retrieved. The main effective components such as quercetin， β-sitosterol， kaempferol， and luteolin， as well as core targets such as IL-6， TNF， IL-1β， PTGS2， and TP53， were identified. GO biological function analysis showed that the treatment of asthma with Danlong Oral Liquid is related to biological processes such as inflammatory response， response to lipopolysaccharide， response to external stimulus，positive regulation of gene expression，enzyme binding，protein binding，and cytokine activity. The KEGG pathway enrichment analysis covered signaling pathways such as Th17/IL-17，TNF，PI3K-Akt，and Toll-like receptors. Molecular docking results showed good affinity between the main effective components and the core targets. Conclusion：Danlong Oral Liquid may regulate multiple signaling pathways such as Th17 cell differentiation，IL-17， TNF， PI3K-Akt， and Toll-like receptors through effective components such as quercetin， β -sitosterol， and kaempferol，acting on core targets such as IL-6，TNF，IL-1β，and PTGS2，and inhibiting the production of various inflammatory cells and cytokines， thereby reducing airway allergic reactions and airway remodeling， ultimately achieving the purpose of treating asthma.