Abstract: Objective: To observe the clinical efficacy of copper bian scraping therapy based on the "ear holography" theory in treating patients with mild to moderate Alzheimer′s disease (AD) accompanied by sleep disorders. Methods:A total of 60 patients with mild to moderate AD accompanied by sleep disorders treated at the Memory Clinic of Guangdong Provincial Hospital of Chinese Medicine from January 202 to August 2024 were randomly divided into the trial group and the control group, with 0 patients in each group, using a random number table method. The control group received sleep health education on the basis of conventional anti-AD treatment,while the trial group received ear holographic copper bian scraping treatment on the basis of the control group,once a week for four consecutive weeks. Before and after treatment, the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality, the Mini Mental State Examination (MMSE) was used to assess cognitive function, and the Zarit Burden Interview (ZBI) was used to assess caregiver burden. Compared the PSQI, MMSE, and ZBI scores of the two groups before and after treatment. Results: After treatment, the PSQI and ZBI scores in both groups were decreased when compared with those before treatment (P<0.05),and the PSQI and ZBI scores in the trial group were lower than those in the control group (P<0.05) . After treatment,the MMSE score in the trial group was increased when compared with that before treatment (P<0.05). Conclusion: The copper bian scraping therapy based on the "ear holography" theory can effectively improve the sleep quality of patients with mild to moderate AD accompanied by sleep disorders, enhance cognitive function,and reduce the burden on caregivers.