基于数据挖掘技术总结刘爱民辨治斑秃用药规律
DOI:
CSTR:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R758.71

基金项目:

河南省中医药科学研究专项课题(20-21ZY2210);第七批全国老中医药专家学术经验继承工作项目(国中医药人教函〔2022〕76号); 第二批河南省中医专科诊疗中心(豫卫中医函〔2024〕2号);河南省第二批中医药青苗人才培养项目(豫卫中医函〔2021〕16号)。


Analysis of LIU Aimin's Medication Rules for Differentiation and Treatment of Alopecia Areata Based on Data Mining Technology
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:以临床治愈病例为基础挖掘刘爱民教授中医药治疗斑秃的用药规律,为临床治疗斑秃提供 参考。方法:通过对刘爱民教授近年来400例门诊斑秃效验医案进行梳理、分析、归纳,运用软件SPSS和 Excel进行数据挖掘,总结刘爱民教授治疗斑秃的临床用药规律。结果:共纳入400首方剂,包含中药154种。 提取出证素6种,以精亏、气虚、血虚及血热为主。病位主要在肝、脾、肾,临床以茯苓、菟丝子、陈皮、当 归、制何首乌、侧柏叶为常用药。药物类别以补虚药为主,药性集中于温、平,药味以甘、辛、苦为主,归经 主要在肝、脾、肾经。关联规则分析显示关联强度较高的组合有9对,系统聚类分析结果分为2类,关联规则 的网络可视化显示节点为60时核心药物为枸杞子、菟丝子、制何首乌、陈皮、茯苓、当归、柴胡、桂枝等 8味,且药物间配伍关联关系较高。结论:刘爱民教授治疗斑秃以肝、脾、肾同调为主,重在温补、淡利、辛 通之品,兼以凉血活血、利水渗湿、理气导滞等药进行治疗。

    Abstract:

    Abstract:Objective:To explore Professor LIU Aimin´s medication rules for the differentiation and treatment of alopecia areata with Chinese medicine based on clinically cured cases, providing a reference for clinical treatment of alopecia areata. Methods:By sorting out,analyzing,and summarizing 400 outpatient cases of alopecia areata treated by Professor LIU Aimin in recent years, data mining was conducted via SPSS and Excel software to summarize the clinical medication rules for the treatment of alopecia areata. Results:A total of 400 prescriptions containing 154 types of Chinese medicinals were included. Six syndrome elements were extracted,with essence deficiency,qi deficiency, blood deficiency,and blood heat being the primary factors. The disease mainly involved the liver,spleen,and kidney. The commonly used Chinese medicinals in clinical practice included Poria, Cuscutae Semen, Citri Reticulatae Pericarpium, Angelicae Sinensis Radix, Polygoni Multiflori Radix Praeparata and Platycladi Cacumen. The main categories of Chinese medicinals used were those for supplementing deficiency, with medicinal properties focused on warm and neutral, and flavors mainly sweet, acrid, and bitter. The channel entries of the Chinese medicinals were mainly on the liver, spleen, and kidney channels. Association rule analysis revealed nine pairs of combinations with high association degree. The results of systematic cluster analysis were divided into two categories. The network visualization of association rules revealed that when the number of nodes was 60, the core Chinese medicinals were Lycii Fructus, Cuscutae Semen, Polygoni Multiflori Radix Praeparata, Citri Reticulatae Pericarpium, Poria, Angelicae Sinensis Radix,Bupleuri Radix and Cinnamomi Ramulus,with a high degree of compatibility among these Chinese medicinals. Conclusion:Professor LIU Aimin´s treats alopecia areata focuses on the simultaneous regulation of the liver, spleen, and kidney, emphasizing the application of the three Chinese medicinals of warming and supplementing, percolating and draining, and unblocking with bitter-acrid medicinals. Supplemented by Chinese medicinals of cooling blood and invigorating blood, promoting urination and percolating dampness, and rectifying qi and removing stagnation.

    参考文献
    相似文献
    引证文献
引用本文

王庆兴,张步鑫,李静,方重阳,徐胜东,武昶宇,刘爱民.基于数据挖掘技术总结刘爱民辨治斑秃用药规律[J].新中医,2025,57(10):14-21

复制
相关视频

分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2025-05-27
  • 出版日期:
文章二维码