Abstract： Professor LYU Zhiping has developed a unique and profound understanding of the physiological and pathological characteristics of the "liver" in Chinese medicine. Integrating academic perspectives from historical physicians， he proposed the clinical philosophy of "regulating the liver and rectifying qi to harmonize the five zangorgans." In clinical practice，Professor LYU Zhiping flexibly employs the method of "regulating the liver and rectifying qi" to treat various internal medical miscellaneous diseases. His core prescriptions—Sini Powder， Chaihu Shugan Powder， and Xiaoyao Powder， collectively termed the "three liver-soothing powder formulations"—are applied with precise syndrome differentiation，yielding reliable therapeutic outcomes.