Abstract:Objective:To sort and analyze the medication rules of Chinese medicine for rheumatism arthralgia by using the Ancient and Modern Medical Case Cloud Platform. Methods: The medical case data on the treatment of rheumatism arthralgia with Chinese medicine were collected from the Ancient and Modern Medical Case Cloud Platform (V2.3.9),the statistical analysis on use frequency,nature,flavors and meridian entries of Chinese medicinals,and tongue manifestation and pulse condition was done, and the cluster analysis and complicated network analysis on highly-used Chinese medicinals were performed. Results: A total of 129 medical cases were included, involving 270 Chinese medicinals, including Cinnamomi Ramulus, Paeoniae Radix Alba, Glycyrrhizae Radix et Rhizoma, Angelicae Sinensis Raix, Astragali Radix, Saposhnikoviae Radix, Coicis Semen and Spatholobi Caulis. The above Chinese medicinals were warm and neutral in flavor,and sweet,astringent and bitter in nature and their main meridian entry is the liver. The cluster analysis suggested five groups of highly-used Chinese medicinals. The first group included Coicis Semen and Atractylodis Rhizoma, the second group Angelicae Sinensis Raix and Astragali Radix, the third group Saposhnikoviae Radix and Gentianae Macrophyllae Radix, the fourth group Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma,and the fifth group Cinnamomi Ramulus and Spatholobi Caulis. The fifth group has the highest confidence level based on the association rule analysis, and the combination of Paeoniae Radix Alba and Cinnamomi Ramulus has the highest support degree. The complex network analysis indicated the combination groups of Paeoniae Radix Alba-Cinnamomi Ramulus and Paeoniae Radix Alba-Glycyrrhizae Radix et Rhizoma with the highest proportion. Conclusion: The therapy of Chinese medicine for rheumatic arthralgia primarily focuses on boosting qi, warming the meridians,and relieving impediment,with nourishing yin and clearing heat as a supplementary approach. The frequently used herbal combinations are similar to those in Huangqi Guizhi Wuwu Decoction, Danggui Buxue Decoction,Guizhi Decoction,and Guizhi Shaoyao Zhimu Decoction.