基于数据挖掘探究中医药治疗风湿病关节痛用药规律
DOI:
CSTR:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R259;R249

基金项目:

中山市社会公益与基础研究项目(2020SYF03);广东省医学科学技术研究基金项目(B2022100);广东省基础与应用基础研究基 金项目(2021A1515220133);中山市科技创新领军人才资助项目(LJ2023001)


Exploration of Medication Rules of Chinese Medicine for Rheumatism Arthralgia Based on Data Mining
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:运用古今医案云平台整理并分析中医药治疗风湿病关节痛的用药规律。方法:收集古今医 案云平台(V2.3.9) 医案库中中医药治疗风湿病关节痛的医案数据,对用药频次、药物性味归经、舌象脉象等 进行统计,对高频药物进行聚类分析及复杂网络分析。结果:共纳入医案129个,涉及中药270味,高频药物 有桂枝、白芍、甘草、当归、黄芪、防风、薏苡仁、鸡血藤。药味以温、平为主;药性以甘、辛、苦为多;主 要归肝经。高频中药系统聚类分析聚为5组,第一组为薏苡仁、苍术;第二组为当归、黄芪;第三组为防风、 秦艽;第四组为白芍、甘草;第五组为桂枝、鸡血藤。药物关联分析得到鸡血藤与桂枝组合的置信度最高,白 芍与桂枝组合支持度最高。复杂网络分析得到白芍-桂枝、白芍-甘草的权重最大。结论:中医药治疗风湿病 关节痛以益气温经通痹为主,滋阴清热为辅,高频用药组成与黄芪桂枝五物汤、当归补血汤、桂枝汤、桂枝芍 药知母汤相类似。

    Abstract:

    Abstract:Objective:To sort and analyze the medication rules of Chinese medicine for rheumatism arthralgia by using the Ancient and Modern Medical Case Cloud Platform. Methods: The medical case data on the treatment of rheumatism arthralgia with Chinese medicine were collected from the Ancient and Modern Medical Case Cloud Platform (V2.3.9),the statistical analysis on use frequency,nature,flavors and meridian entries of Chinese medicinals,and tongue manifestation and pulse condition was done, and the cluster analysis and complicated network analysis on highly-used Chinese medicinals were performed. Results: A total of 129 medical cases were included, involving 270 Chinese medicinals, including Cinnamomi Ramulus, Paeoniae Radix Alba, Glycyrrhizae Radix et Rhizoma, Angelicae Sinensis Raix, Astragali Radix, Saposhnikoviae Radix, Coicis Semen and Spatholobi Caulis. The above Chinese medicinals were warm and neutral in flavor,and sweet,astringent and bitter in nature and their main meridian entry is the liver. The cluster analysis suggested five groups of highly-used Chinese medicinals. The first group included Coicis Semen and Atractylodis Rhizoma, the second group Angelicae Sinensis Raix and Astragali Radix, the third group Saposhnikoviae Radix and Gentianae Macrophyllae Radix, the fourth group Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma,and the fifth group Cinnamomi Ramulus and Spatholobi Caulis. The fifth group has the highest confidence level based on the association rule analysis, and the combination of Paeoniae Radix Alba and Cinnamomi Ramulus has the highest support degree. The complex network analysis indicated the combination groups of Paeoniae Radix Alba-Cinnamomi Ramulus and Paeoniae Radix Alba-Glycyrrhizae Radix et Rhizoma with the highest proportion. Conclusion: The therapy of Chinese medicine for rheumatic arthralgia primarily focuses on boosting qi, warming the meridians,and relieving impediment,with nourishing yin and clearing heat as a supplementary approach. The frequently used herbal combinations are similar to those in Huangqi Guizhi Wuwu Decoction, Danggui Buxue Decoction,Guizhi Decoction,and Guizhi Shaoyao Zhimu Decoction.

    参考文献
    相似文献
    引证文献
引用本文

陈诚霖,刘卓华,陈亮.基于数据挖掘探究中医药治疗风湿病关节痛用药规律[J].新中医,2025,57(11):7-12

复制
分享
相关视频

文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2025-06-13
  • 出版日期:
文章二维码