Abstract: Objective: To analyze the syndrome types and medication rules of Chinese medicine for pediatric enuresis using data mining technology. Methods: We searched for literature on the treatment of pediatric enuresis with Chinese medicine from the inception of the databases to October 31, 2024, in the China National Knowledge Infrastructure( CNKI),China Online Journals( COJ),and Chinese Science and Technology Journal Database( CSTJ). The syndrome types and the composition of Chinese medicine prescriptions were recorded. The usage frequency and the nature, flavor, and meridian tropism of the medicinals were counted. Association rule analysis and cluster analysis were performed on the high-frequency medicinals with a usage frequency of ≥20 times. Results:A total of 148 articles were included, covering 38 syndrome types, with the main ones being kidney qi insecurity syndrome, bladder deficiency-cold syndrome, spleen-lung deficiency syndrome, and spleen-kidney deficiency syndrome. There were 152 Chinese medicine prescriptions involving 191 different medicinals. A total of 27 medicinals had a usage frequency of ≥20 times,with the top five being Alpiniae Oxyphyllae Fructus,Mantidis Oötheca,Dioscoreae Rhizoma,Linderae Radix, and Acori Tatarinowii Rhizoma. The top three therapeutic categories were tonifying, astringent, and qiregulating medicinals. The top three natures were warm,neutral,and slightly cold. The top three flavors were sweet, pungent, and bitter. The top three meridian tropism were kidney, spleen, and lung. Association rule analysis identified six sets of strongly associated medicinal combinations. Cluster analysis identified nine commonly used medicinal couplets and four core combinations. Conclusion: Common syndrome types in pediatric enuresis include kidney qi insecurity syndrome, bladder deficiency-cold syndrome, and spleen-lung deficiency syndrome. In clinical practice,Chinese medicine focuses on warming and supplementing kidney qi and consolidating the bladder,combined with tonifying the spleen and supplementing the lung.