基于数据挖掘分析何迎春治疗失眠用药规律
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R256.23

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浙江省中医药科技计划项目(2023ZF143)


Analysis of HE Yingchun's Medication Rules in the Treatment of Insomnia Based on Data Mining
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    摘要:

    目的:基于数据挖掘技术分析何迎春教授治疗失眠的药物组方及用药思路。方法:收集2023年 8月—2024年2月何教授在杭州市中医院门诊诊治失眠医案。运用Excel整理医案信息(包括中药频率、性味归 经等),建立数据库。运用SPSS软件及Apriori算法进行数据统计分析,分析何教授治疗失眠的用药规律。结 果:共纳入 133 首处方,整理中药 147 味,总频次共 2 279 次。使用频次超过 40 次及以上的中药有 23 种, 前 5位是茯苓、大枣、桂枝、合欢皮、生姜。147味中药性味归经统计显示,中药药性以温、寒、平为主,药 味以甘、辛、苦为主,归经以肝经、脾经、肺经、胃经、心经、肾经为主。聚类分析得到 5个核心药物组 合:①煅牡蛎、煅龙骨、淮小麦、黄芩、醋北柴胡、党参、炙甘草、大枣、桂枝、炒白芍;②生姜、姜半夏、 茯苓、黄连、肉桂、姜竹茹、合欢皮、郁金;③煅磁石、煅珍珠母;④酸枣仁粉、灵芝;⑤桑白皮。结论:何 教授治疗失眠多从肝脾论治,注重补虚泻实,调和阴阳,标本兼治。

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    Abstract:Objective:To analyze Professor HE Yingchun's medication prescriptions and strategies for treating insomnia using data mining technology. Methods:Medical records of insomnia patients from Professor HE's outpatient clinic at Hangzhou Hospital of Traditional Chinese Medicine between August 2023 and February 2024 were collected. Information such as herbal use frequency,natures,flavors,and channel entries was organized via Excel to establish a database. SPSS software and the Apriori algorithm were applied for statistical analysis to identify medication rules. Results:A total of 133 prescriptions and 147 Chinese herbs were analyzed,with a cumulative frequency of 2 279 uses. A total of Chinese herbs were used over 40 times, with the top five being Poria, Jujubae Fructus, Cinnamomi Ramulus,Albiziae Cortex,and Zingiberis Rhizoma Recens. Analysis of the 147 Chinese herbs revealed that their natures were predominantly warm, cold, or neutral; flavors were mainly sweet, acrid, or bitter; and channel entries were the liver,spleen,lung,stomach,heart,and kidney channels. Cluster analysis identified five core herbal combinations:1) calcined Ostreae Concha,calcined Fossilia Ossis Mastodi,Fructus Tritici in Jianghuai Area, Scutellariae Radix, vinegar-processed Bupleuri Radix, Codonopsis Radix, Glycyrrhizae Radix et Rhizoma Praeparata cum Melle,Jujubae Fructus,Cinnamomi Ramulus,and stir-fried Paeoniae Radix Alba;2) Zingiberis Rhizoma Recens,Pinelliae Rhizoma Praeparatum cum Zingibere et Alumine,Poria,Coptidis Rhizoma,Cinnamomi Cortex,ginger-processed Bambusae Caulis in Taenias,Albiziae Cortex,and Curcumae Radix;3) calcined Magnetitum and calcined Margaritifera Concha;4) Ziziphi Spinosae Semen Powder and Ganoderma;5) Mori Cortex. Conclusion: Professor HE's treatment of insomnia emphasizes from the pespective of the liver-spleen theory, focusing on supplementing deficiency and draining excess,harmonizing yin and yang,and addressing both the root and branch of the condition.

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惠扬,黄小哲,指导:何迎春.基于数据挖掘分析何迎春治疗失眠用药规律[J].新中医,2025,57(13):1-5

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  • 在线发布日期: 2025-07-14
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