Abstract：Objective：To investigate the medication rules of Chinese medicine for androgenetic alopecia （AGA） based on real-world data. Methods： A single research center collected outpatient cases of AGA treated at the Department of Dermatology in Shenzhen Traditional Chinese Medicine Hospital from November 1，2022，to November 30，2023，meeting inclusion and exclusion criteria. A database was established using Excel 2016，and SPSS Modeler 20， SPSS Statistics 26.0， and Cytoscape were employed to analyze gender， age， her buse frequency， syndrome types，herb natures，herb flavors，channel entries，efficacy categories，association rule analysis，and hierarchical cluster analysis. Results：A total of 190 cases were included，involving 136 herbs across 190 prescriptions. Twenty core herbs with a frequency ≥30 were identified， with Poria being the most frequent， followed by Atractylodis Macrocephalae Rhizoma，Salviae Miltiorrhizae Radix et Rhizoma，and Citri Reticulatae Pericarpium. The predominant syndromes were spleen-kidney deficiency，followed by damp-heat accumulation in the spleen and spleen deficiency with damp retention. Herb natures were predominantly neutral，flavors were mainly sweet and bitter，and channel entries targeted the spleen，liver，stomach，lung，and kidney channels. The most common efficacy categories were qi- supplementing herbs， diuresis-inducing and swelling-dispersing herbs， and qi-regulating herbs. Association rule analysis revealed 30 herb pairs with support ≥ 50% and confidence ≥ 80%， such as Atractylodis Macrocephalae Rhizoma-Poria，Salviae Miltiorrhizae Radix et Rhizoma-Poria，Salviae Miltiorrhizae Radix et Rhizoma-Atractylodis Macrocephalae Rhizoma. Cluster analysis identified three distinct clusters. Conclusion：The treatment of AGA focuses on constitutional deficiency （root） as the framework and excess syndromes （branch） as the target. Oral herbal prescriptions primarily include tonifying herbs and diuresis-inducing and dampness-draining herbs. The herbs are predominantly sweet and neutral in flavors and natures， with channel entries associated with the spleen， liver， stomach， lung， and kidney channels. AGA pathogenesis is linked to liver-kidney insufficiency， damp-heat accumulation in the spleen，and spleen deficiency with damp retention. Core therapeutic strategies involve tonifying the liver and kidney，clearing damp-heat，and strengthening the spleen to resolve dampness.