Abstract：Objective：To observe the curative effect of the combination use of Shengyang Sanhan Decoction and acupoint application on Raynaud's syndrome. Methods：A total of 70 patients with Raynaud's syndrome admitted to Linhai Hospital of Traditional Chinese Medicine from January 2018 to December 2022 were selected and divided into the control group and the observation group according to different treatment methods，with 35 cases in each group. The control group was treated with western medicine， and the observation group was treated with Shengyang Sanhan Decoction combined with acupoint application on the basis of the treatment in the control group. The clinical effects， and the changes in the duration of Raynaud's phenomenon，cold water test，fist test，and the levels of hemorheology [hematocrit（HCT） and plasma viscosity （PV）] and immunoglobulin [immunoglobulin M （IgM）， immunoglobulin G （IgG） and immunoglobulin A （IgA）] were respectively compared between the two groups. Results：After four weeks of treatment，the total effective rate was 94.29% （33/35） in the observation group and 71.43% （25/35） in the control group，with a statistically significant difference （P＜0.05）. After four weeks of treatment，the duration of paleness， cyanosis and redness of fingers，and pain and numbness in the two groups were reduced when compared with those before treatment （P＜0.05），and the duration of paleness，cyanosis and redness of fingers，and pain and numbness in the observation group were shorter than those in the control group （P＜0.05）. After four weeks of treatment，the positive rates of fist test and cold water test in the two groups were lower than those before treatment （P＜0.05），and the positive rates of fist test and cold water test in the observation group were lower than those in the control group （P＜0.05）. After four weeks of treatment，the levels of HCT and PV in the two groups were dwindled when compared with those before treatment （P＜0.05），and the above two levels in the observation group were lower than those in the control group （P＜ 0.05）. After four weeks of treatment，the levels of IgM，IgG and IgA in the two groups were down-regulated when compared with those before treatment （P＜0.05），and the above three levels in the observation group were lower than those in the control group （P＜0.05）. Conclusion：The combination use of Shengyang Sanhan Decoction and acupoint application has a good clinical effect on Raynaud's syndrome， which can relieve the symptoms and improve the hemorheology and the immune function.