Abstract： Objective： To observe the curative effect of the combination use of Sijunzi Decoction and Sanzi Yangqin Decoction on stable chronic obstructive pulmonary disease（COPD）of turbid phlegm obstructing lung type. Methods：A total of 134 patients with stable COPD of turbid phlegm obstructing lung type admitted to Shaoxing City Keqiao District Traditional Chinese Medicine Hospital Medical Alliance Central Hospital from November 2023 to August 2024 were divided into the observation group（68 cases）and the control group（66 cases）according to various treatment plan. The control group was treated with western medicine， and the observation group was additionally treated with Sijunzi Decoction combined with Sanzi Yangqin Decoction based on the treatment in the control group. Both groups were treated for four weeks continuously. The clinical effects and incidence of adverse reactions，and the changes before and after treatment in traditional Chinese medicine syndrome scores， lung function indexes [maximal voluntary ventilation （MVV）， forced expiratory volume in one second（FEV1） and forced expiratory volume in one second percentage predicted （FEV1%）]， airway remodeling indexes [matrix metalloproteinase-9 （MMP-9）， tissue inhibitor of metalloproteinase-1（TIMP-1）and vascular endothelial growth factor（VEGF）] and the levels of serum inflammatory factors [interleukin-1α（IL-1α）， interleukin-17（IL-17）and tumor necrosis factor-α（TNF-α）] were respectively compared between the two groups. Results： The clinical effects in the observation group were better than that in the control group，the difference being significant（P＜0.05）. After treatment，the traditional Chinese medicine syndrome scores of main and secondary symptoms in the two groups were decreased when compared with those before treatment （P＜0.05），and the above scores in the observation group were lower than those in the control group（P＜0.05）. After treatment， the levels of MVV， FEV1% and FEV1 in the two groups were increased when compared with those before treatment， and the levels of above three indexes in the observation group were higher than those in the control group （P＜0.05）. After treatment， the levels of MMP-9 and VEGF in the two groups were decreased when compared with those before treatment（P＜0.05），and the TIMP-1 levels in the two groups were elevated when compared with those before treatment（P＜0.05）； the levels of MMP-9 and VEGF in the observation group were lower than those in the control group（P＜0.05），and the TIMP-1 level was higher than that in the control group（P＜0.05）. After treatment， the levels of IL-1α，IL-17 and TNF-α in the two groups dwindled when compared with those before treatment，and the above three levels in the observation group were lower than those in the control group（P＜0.05）. The incidence of adverse reactions was 10.29%（7/68）in the observation group and 9.09%（6/66）in the control group，there being no significance in the difference（P＞0.05）. Conclusion： The combination use of Sijunzi Decoction and Sanzi Yangqin Decoction has a good clinical effect on stable COPD with syndrome of turbid phlegm obstructing lung， which can improve the airway remodeling and degree of body inflammation，and promote the lung function.