Abstract:Abstract: Objective: To observe the clinical effect of kidney-warming and stasis-dissolving therapy based on menstrual phases in treating uterine adenomyosis.Methods:A total of 100 uterine adenomyosis patients treated at the Inpatient Department of Gynecology, Shengzhou Traditional Chinese Medicine Hospital from October 2022 to September 2024 were collected and randomly divided into a trial group and a control group,with 50 cases in each group using block randomization.The control group was treated with Shaofu Zhuyu Decoction,while the trial group received kidney-warming and stasis-dissolving therapy(administering Huayu Prescription from three days before menstruation until the end of the menstrual period and kidney-warming Prescription during the intermenstrual period).The treatment lasted for three menstrual cycles.Hemorheological parameters [whole blood high shear viscosity(200/s),whole blood low shear viscosity(1 / s), and plasma viscosity], dysmenorrhea severity scores, traditional Chinese medicine syndrome scores, Visual Analogue Scale(VAS)for pain, uterine volume, and carbohydrate antigen 125(CA125) levels were compared before and after treatment between the two groups.Results:After treatment,the total effective rate was 88.00%(44/50)in the trial group and 78.00%(39/50)in the control group, with no significance in the difference(P>0.05).The cured and markedly improved rate was 52.00% (26/50) in the trial group and 32.00% (16/50) in the control group, with significance in the difference(P<0.05).In both groups, whole blood high shear viscosity, whole blood low shear viscosity,and plasma viscosity were decreased compared to before treatment(P<0.05),with the trial group showing lower levels in all three parameters(P<0.05). Dysmenorrhea severity scores, traditional Chinese medicine syndrome scores,and VAS scores were decreased in both groups after treatment(P<0.05),with the trial group having lower scores than the control group(P<0.05).After treatment,the uterine volume in the trial group decreased compared to before treatment(P<0.05) and was smaller than that of the control group(P<0.05). In contrast,no statistically significant difference was observed in the control group before and after treatment(P>0.05). CA125 levels in both groups reduced compared to before treatment(P<0.05),with the trial group showing lower levels than the control group(P<0.05). Conclusion: Kidney-warming and stasis-dissolving therapy based on menstrual phases can effectively alleviate clinical symptoms of uterine adenomyosis, reduce pain, shrink uterine volume, and improve hemorheological and serum CA125 levels.