Abstract： Objective： To observe the clinical efficacy of Eight-Trigram scalp acupuncture combined with auricular point taping therapy in the treatment of post-stroke insomnia． Methods： Sixty patients with post-stroke insomnia treated at Wenzhou People's Hospital from January to October 2024 were enrolled and divided into the trial group and the control group using the random number table method，with 30 cases in each group．Both groups received auricular point taping therapy．The control group additionally received conventional acupuncture，while the trial group received Eight-Trigram scalp acupuncture．Treatment lasted for four weeks for both groups．Clinical efficacy，sleep quality，neurological function，neurotransmitter levels，and incidence of adverse reactions were compared．Results： After four weeks of treatment，the total effective rate in the trial group was 93.33%（28/30），significantly higher than that of 70.00%（21/30）in the control group（P＜0.05）．Scores of Pittsburgh Sleep Quality Index（PSQI）and National Institutes of Health Stroke Scale（NIHSS）in the two groups decreased compared with those before treatment， with significantly lower scores in the trial group（P＜0.05）． Levels of 5-hydroxytryptamine（5-HT）and γ-aminobutyric acid（GABA）in the two groups increased compared with those before treatment，while dopamine（DA）decreased（P＜ 0.05）；the trial group showed significantly higher 5-HT and GABA levels and lower DA levels than the control group （P＜0.05）．During the treatment period，the incidence of adverse reactions was 13.33%（4/30）in the trial group and 6.67%（2/30）in the control group，showing no significant difference（P＞0.05）．Conclusion：Eight-Trigram scalp acupuncture combined with auricular point taping therapy effectively improves sleep quality and neurological function in patients with post-stroke insomnia，exerts certain efficacy and favorable safety.