针刺联合肺康复锻炼对肺癌合并轻度慢性阻塞性肺疾病肺脾气虚证患者术后康复的影响
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R246.5;R563

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潍坊市卫生健康委员会中医药科研项目(WFZYY2023-3-012);山东第二医科大学附属医院院校联合课题(2024FYM001)


Effect of Acupuncture Combined with Pulmonary Rehabilitation Exercise on Postopera⁃ tive Recovery of Lung Cancer Patients Complicated with Mild COPD with Lung-Spleen Qi Deficiency Syndrome
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    摘要:

    目的:观察针刺联合肺康复锻炼对肺癌合并轻度慢性阻塞性肺疾病(COPD) 肺脾气虚证患者术后 康复的影响。方法:选取2023年6月—2024年10月山东第二医科大学附属医院收治的108例肺癌合并轻度 COPD肺脾气虚证患者,根据随机数字表法分为对照组及观察组,每组54例。2组均在手术后当天即开始进行 雾化吸入治疗,在此基础上,对照组予肺康复锻炼治疗,观察组则予针刺联合肺康复锻炼治疗。观察2组入院 当天、术后1个月肺功能和运动耐量以及入院当天、术后第5天炎症指标的变化情况,比较2组术后并发症发 生率、胸腔闭式引留置时间及住院时间。结果:术后1个月,2组用力肺活量(FVC)、第1秒用力呼气容积 (FEV1)、最大通气量(MVV) 水平均较入院当天降低(P<0.05),6 min步行试验(6MWT) 距离均较入院当 天缩短(P<0.05);观察组FVC、FEV1水平均高于对照组(P<0.05),6MWT距离长于对照组(P<0.05)。术后 第5天,2组肿瘤坏死因子-α(TNF-α)、C-反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10) 水平均较入院当天升高(P<0.05),观察组TNF-α、CRP、IL-6水平均低于对照组(P<0.05),观察组IL-10 水平高于对照组(P<0.05)。观察组术后肺部感染、肺不张发生率均低于对照组(P<0.05),胸腔引流管留置 时间短于对照组(P<0.05)。2组心律失常发生率及住院时间比较,差异均无统计学意义(P>0.05)。结论: 针刺联合肺康复锻炼能提升肺癌合并轻度COPD肺脾气虚证患者术后的康复效果,降低术后并发症发生率。

    Abstract:

    Abstract: Objective: To observe the effect of acupuncture combined with pulmonary rehabilitation exercise on postoperative recovery in lung cancer patients complicated with mild chronic obstructive pulmonary disease(COPD) with lung-spleen qi deficiency syndrome.Methods:A total of 108 lung cancer patients complicated with mild COPD with lung-spleen qi deficiency syndrome admitted to the Affiliated Hospital of Shandong Second Medical University between June 2023 and October 2024 were divided into the control group and the observation group using the random number table method,with 54 cases in each group.Both groups received aerosol inhalation therapy starting on the day of surgery. The control group received pulmonary rehabilitation exercise, while the observation group received acupuncture combined with pulmonary rehabilitation exercise. Lung function, exercise tolerance were observed on admission day and at one month postoperatively, while inflammatory markers were assessed on admission day and postoperative day five. Incidence of postoperative complications, duration of thoracic drainaga tube placement and hospital stay were compared between the two groups. Results: At one month postoperatively, forced vital capacity (FVC), forced expiratory volume in one second(FEV1), and maximum voluntary ventilation(MVV) decreased compared with those on the admission day(P<0.05),6-minute walk test(6MWT)distance was shortened compared with that on the admission day in both groups(P<0.05).The observation group showed higher FVC and FEV1 levels (P<0.05)and longer 6MWT distance(P<0.05)than the control group. On postoperative day five, tumor necrosis factor-α(TNF-α), C-reactive protein(CRP), interleukin-6(IL-6), and interleukin-10(IL-10)levels were elevated compared with those on the admission day in both groups(P<0.05).The observation group demonstrated lower TNF-α,CRP,and IL-6 levels(P<0.05)but higher IL-10 levels(P<0.05)than the control group.The observation group had lower incidences of postoperative pulmonary infection and atelectasis(P<0.05), and shorter duration of thoracic drainage tube placement(P<0.05).No significant differenceswerefoundinarrhythmiaincidenceorhospitalstay betweenthetwogroups(P>0.05).Conclusion:Acupuncture combined with pulmonary rehabilitation exercise enhances postoperative recovery and reduces the incidence of postoperative complications in lung cancer patients with mild COPD with lung-spleen qi deficiency syndrome.

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赵阳,陶慧鑫,王爱英,王志鹏.针刺联合肺康复锻炼对肺癌合并轻度慢性阻塞性肺疾病肺脾气虚证患者术后康复的影响[J].新中医,2025,57(18):159-163

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  • 在线发布日期: 2025-09-25
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