Abstract: Objective: To analyze the medication rules of topical Chinese herbal medicine for hyperosteogeny using data mining techniques. Methods: Prescriptions for topical Chinese herbal medicine in the treatment of hyperosteogeny were collected from China National Knowledge Infrastructure (CNKI), China Science Periodical Database(CSPD),and China Science and Technology Journal Database(VIP). R language was employed to analyze high-frequency herbs,dosage form distribution,herbal efficacy,properties,flavor,and meridian tropism,to mine the association rules of herbal medicine, and to perform hierarchical cluster analysis for identifying core herbal combinations. Results: A total of 98 prescriptions were included, among which the aqueous preparations were the primary dosage form of topical Chinese herbal medicine,with fumigation-washing preparations accounting for the most. High-frequency herbs included Carthami Flos, Clematidis Radix et Rhizoma, and Speranskiae Tuberculatae Herba, etc., whose primary efficacies were activating blood and removing stasis, expelling wind and eliminating dampness, and releasing the exterior,medicinal properties were predominantly warm,flavors were mainly bitter and pungent and meridian tropisms targeted the liver, spleen, stomach, and kidney meridians. Association rule analysis revealed Olibanum-Myrrha and Aconiti Radix-Aconiti Kusnezoffii Radix as key couplet medicinals. Significant triplet medicinals included Carthami Flos-Aconiti Kusnezoffii Radix-Persicae Semen and Carthami Flos-Olibanum-Persicae Semen. Cluster analysis categorized high-frequency herbs into six groups, reflecting the formulation strategies of eliminating pathogens, reinforcing healthy qi, and combating refractory conditions. Conclusion: Topical Chinese herbal medicine for hyperosteogeny emphasizes core principles of activating blood and promoting qi circulation,expelling wind and eliminating dampness, and tonifying the liver and kidney. Core herbs such as Carthami Flos, Persicae Semen, Olibanum,Myrrha,Aconiti Kusnezoffii Radix,and Aconiti Radix are widely used. The combination of Olibanum and Myrrha demonstrates particularly notable efficacy in detoxifying,reducing swelling,and alleviating pain.