基于数据挖掘技术分析欧阳永红诊治慢性萎缩性胃炎肝郁脾虚证用药规律
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Analysis of Medication Patterns in the Treatment of Chronic Atrophic Gastritis with Liver Qi Stagnation and Spleen Deficiency Syndrome by OUYANG Yonghong Using Data Mining Techniques
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    摘要:

    目的:基于数据挖掘技术研究欧阳永红治疗慢性萎缩性胃炎(CAG) 肝郁脾虚证的用药规律。 方法:采集2023年2月1日—2024年7月31日在欧阳永红门诊治疗有效的CAG患者医案,将医案数据通过古 今医案云平台、SPSS Modeler 18.0、SPSS Statistics 26.0及Excel 2016软件统计中药频数、性味、归经,进行关 联规则分析、复杂网络分析及聚类分析。结果:本研究纳入治疗有效的CAG肝郁脾虚证医案共313例,涉及中 药161味,中药出现总频次为5 519次,其中频次≥0.7%的药物(高频药物) 有32味,药性频次前3位依次是 温、平、微寒,药味频次前3位依次是甘、苦、辛,归经频次前4位依次是脾、肺、胃、肝经。高频药物经关 联规则分析得到3组核心药对,经复杂网络分析得到8个核心药物,经聚类分析得出6个聚类方,其中核心聚 类方为:党参、佛手、香附、紫苏梗、柴胡、郁金、砂仁、枳实。结论:基于数据挖掘技术研究欧阳永红治疗 CAG肝郁脾虚证的用药规律,以健脾疏肝为基本治则,兼杂痰浊、热毒、血瘀时,辅以化痰散结、清热解毒、 活血通络。

    Abstract:

    Abstract: Objective: To investigate the medication patterns used by OUYANG Yonghong in treating chronic atrophic gastritis (CAG) with liver qi stagnation and spleen deficiency syndrome using data mining techniques. Methods:Medical records of patients with CAG who were effectively treated by OUYANG Yonghong between February 1,2023,and July 31,2024,were collected. Data from these records were analyzed using the Ancient and Modern Medical Case Cloud Platform,SPSS Modeler 18.0,SPSS Statistics 26.0,and Excel 2016 to determine the frequency of use of Chinese medicines, their properties, flavors, and meridian tropism. Association rule analysis, complex network analysis,and cluster analysis were also performed. Results:A total of 313 medical records of patients with CAG with liver qi stagnation and spleen deficiency syndrome were included in this study, involving 161 Chinese medicines with a total frequency of 5 519 times. Among them,32 medicines with a frequency of ≥0.7%(high-frequency medicines)were identified. The top three properties were warm,neutral,and slightly cold,while the top three flavors were sweet, bitter, and pungent. The top four meridians were spleen, lung, stomach, and liver. Association rule analysis of high-frequency medicines identified three core medicine pairs, complex network analysis identified eight core medicines, and cluster analysis yielded six clustered prescriptions, with the core clustered prescription being: Codonopsis Radix,Citri Sarcodactylis Fructus,Cyperi Rhizoma,Perillae Caulis,Bupleuri Radix,Curcumae Radix, Amomi Fructus, and Aurantii Fructus Immaturus. Conclusion: Based on data mining techniques, this study investigated the medication patterns used by OUYANG Yonghong in treating CAG with liver qi stagnation and spleen deficiency syndrome. The basic therapeutic principle is to tonify the spleen and soothe the liver, supplemented by phlegm-dissipating and mass-dispelling, heat-clearing and detoxifying, and blood-activating and collateralsunblocking when phlegm-turbidity,heat-toxin,and blood stasis are present.

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肖雪芹,冯祥兴.基于数据挖掘技术分析欧阳永红诊治慢性萎缩性胃炎肝郁脾虚证用药规律[J].新中医,2025,57(19):26-32

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  • 在线发布日期: 2025-10-20
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