Abstract：Objective：To analyze the action mechanism of Jiedu Shengshi Decoction in treating viral pneumonia using network pharmacology and molecular docking techniques. Methods：The Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform（TCMSP） was used to obtain the active components of the Chinese medicine. Disease-related genes were retrieved from the GeneCards and OMIM databases； intersection analysis was performed between the Chinese medicine genes and disease genes； the STRING platform was used to construct a protein-protein interaction（PPI）network，and Cytoscape software was used to analyze the common genes；the DAVID platform was employed for Gene Ontology（GO）functional analysis and Kyoto Encyclopedia of Genes and Genomes （KEGG）pathway enrichment analysis of the intersecting genes. AutoDock Tools and POCASA software were used for molecular docking to verify the accuracy of the analysis results. Results：A total of 69 active components and 246 target genes of the Chinese medicine were identified，with 191 intersecting drug-disease targets；five core components were identified：quercetin，kaempferol，β-sitosterol，stigmasterol，and luteolin. Key targets included tumor protein p53 （TP53）， JUN proto-oncogene（JUN）， serine/threonine protein kinase 1（AKT1）， tumor necrosis factor（TNF）， interleukin（IL）-6 ，mitogen-activated protein kinase 3（MAPK3），mitogen-activated protein kinase 1（MAPK1）， caspase-3（CASP3），IL-1β，and FOS. GO analysis indicated that the biological processes involved in the treatment of viral pneumonia with Jiedu Shengshi Decoction were mainly enriched in signal transduction，positive regulation of gene expression，negative regulation of the apoptotic process，response to external stimuli，inflammatory response，positive regulation of cell proliferation，positive regulation of cell apoptosis，response to lipopolysaccharide，and response to hypoxia. KEGG pathway analysis showed enrichment in MAPK signaling pathway， PI3K-AKT signaling pathway， NF -κB signaling pathway， among others. Molecular docking demonstrated good docking activity between the core components and key targets. Conclusion： The action mechanism of Jiedu Shengshi Decoction in treating viral pneumonia may involve active components such as quercetin， luteolin， and stigmasterol acting on key targets like AKT1， IL-6， TNF， JUN， and TP53 through signaling pathways such as MAPK and PI3K-AKT/AKT， affecting multiple biological processes including signal transduction，inflammatory response，and apoptosis regulation.