Abstract：Objective：To observe the clinical effect of atomization fumigation of Rhinitis Fumigation and Washing Prescription combined with oral administration of Rhinitis Prescription on children with allergic rhinitis（AR）of spleenstomach damp-heat type. Methods：A total of 60 cases of AR children of spleen-stomach damp-heat type who were treated at The Affiliated Guangzhou Traditional Chinese Medicine Hospital of Guangzhou University of Chinese Medicine from January to December 2024 were selected and divided into the control group and the treatment group according to the random number table method，with 30 cases in each group. During the treatment period，one case in the control group was lost to follow -up， while there was no dropout in the treatment group. The control group was given the oral administration of Cetirizine Hydrochloride Oral Solution， and the treatment group was treated with atomization fumigation of Rhinitis Fumigation and Washing Prescription combined with oral administration of Rhinitis Prescription. Both groups were treated for two weeks. Traditional Chinese medicine syndrome scores and laboratory indicators [immunoglobulin（Ig）E， interleukin-6（IL-6）， eosinophils（EOS）] levels before and after treatment， as well as clinical effects and safety，were compared between the two groups. Results：After treatment，the total effective rate was 93.33%（28/30）in the treatment group and 72.41%（21/29）in the control group， with a significant difference between the two groups（P＜0.05）. After treatment，both groups showed a decrease in primary and secondary symptom scores compared to before treatment（P＜0.05），with the treatment group showing lower secondary symptom scores than the control group（P＜0.05）， while there was no significant difference in primary symptom scores between the two groups（P＞0.05）. After treatment， both groups showed a decrease in nasal turbinate sign scores compared to before treatment（P＜0.05），but there was no significant difference in nasal turbinate sign scores between the two groups（P＞ 0.05）. After treatment， both groups showed a decrease in the levels of IgE， IL-6， and EOS compared to before treatment（P＜0.05），with the treatment group showing lower levels of all three indicators than the control group（P＜ 0.05）. During the treatment period， no significant adverse reaction was observed in either group. Conclusion： The atomization fumigation of Rhinitis Fumigation and Washing Prescription combined with Rhinitis Prescription has a significant curative effect in treating AR of spleen-stomach damp-heat type，which can effectively reduce inflammatory responses and improve traditional Chinese medicine syndromes，nasal turbinate signs，and immune function.