Abstract： Objective： To observe the clinical efficacy of musculoskeletal ultrasound-guided stellate ganglion block（SGB）combined with electroacupuncture as an adjunct to conventional therapy for post-stroke shoulder-hand syndrome（SHS）. Methods： A total of 80 patients with stage Ⅰ and Ⅱ post-stroke SHS of qi stagnation and blood stasis type treated at Lanxi Hospital of Traditional Chinese Medicine from May 2023 to July 2024 were divided into the SGB group（40 cases）and the combination group（40 cases）using the random number table method. Both groups received conventional therapy，with the SGB group additionally receiving ultrasound-guided SGB and the combination group receiving both ultrasound-guided SGB and electroacupuncture for two weeks. Outcomes included palm circumference improvement rate， clinical efficacy， as well as Visual Analogue Scale（VAS）score for pain， Fugl- Meyer Assessment（FMA）upper extremity score， shoulder range of motion（ROM）in flexion/extension/abduction， and surface electromyography（sEMG）values of triceps and posterior deltoid muscles before and after treatment were compared. Adverse events were monitored. Results： After two weeks of treatment， the total effective rate and the improvement rate of palm circumference in the combination group were higher than those in the SGB group（P＜0.05）. The VAS scores in the two groups were lower than those before treatment（P＜0.05），and the FMA upper limb scores were higher than those before treatment（P＜0.05）. The VAS score in the combination group was lower than that in the SGB group（P＜0.05），and the FMA upper limb score in the combination group was higher than that in the SGB group （P＜0.05）. The ROM of shoulder flexion， extension and abduction in the two groups increased compared with that before treatment（P＜0.05），and the ROM of shoulder flexion，extension and abduction in the combination group was greater than that in the SGB group（P＜0.05）. The sEMG values of triceps and posterior deltoid muscles in the two groups were higher than those before treatment（P＜0.05）， and the sEMG values of triceps and posterior deltoid muscles in the combination group were higher than those in the SGB group（P＜0.05）. No obvious adverse reactions occurred in the two groups. Conclusion：The combination of ultrasound-guided SGB and electroacupuncture effectively reduces hand edema and limb pain，improves shoulder mobility and neuromuscular function of the affected limb instage ⅠandⅡpost-strokeSHSpatientsofqistagnationandbloodstasistype，demonstrating high safety.