前列逐癃汤联合经尿道前列腺等离子电切术对前列腺增生术后排尿功能及并发症的影响
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R699.8

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2022年浙江省医学会临床科研基金项目(2022ZYC-A88)


Effect of Qianlie Zhulong Decoction Combined with Transurethral Plasmakinetic Resection of Prostate on Urinary Function and Complications After Surgery of Prostatic Hyperplasia
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    摘要:

    目的:观察前列逐癃汤联合经尿道前列腺等离子电切术对前列腺增生术后排尿功能及并发症的影 响。方法:选取2022年7月—2024年12月诸暨市中医医院收治的110例前列腺增生患者,按治疗方式不同分 为研究组及对照组各55例。对照组接受常规经尿道前列腺等离子电切术,研究组在对照组基础上给予口服前 列逐癃汤治疗。比较2组治疗前后排尿功能指标值、血清性激素[睾酮(T)、黄体生成素(LH)、促卵泡生成 素(FSH)] 水平、炎性因子[C-反应蛋白(CRP)、白细胞介素-6(IL-6)] 水平的变化,比较2组并发症发 生率。结果:治疗后,2组前列腺体积及膀胱残留尿量均较治疗前减少(P<0.05),最大尿流量均较治疗前增 加(P<0.05);研究组前列腺体积及膀胱残留尿量均低于对照组,最大尿流量高于对照组(P<0.05)。治疗 后,2组T水平均较治疗前升高(P<0.05),LH、FSH水平均较治疗前下降(P<0.05);研究组T水平高于对 照组(P<0.05),LH、FSH 水平均低于对照组(P<0.05)。治疗后,2 组CRP、IL-6 水平均较治疗前上升 (P<0.05),研究组CRP、IL-6水平均低于对照组(P<0.05)。研究组并发症发生率为7.27%(4/55),对照组 并发症发生率为23.64%(13/55),2组并发症发生率比较,差异有统计学意义(P<0.05)。结论:前列逐癃汤 联合经尿道前列腺等离子电切术能改善前列腺增生患者术后排尿功能及血清性激素水平,降低炎性因子及并发 症发生率。

    Abstract:

    Abstract: Objective: To observe the effect of the combination of Qianlie Zhulong Decoction and transurethral plasmakinetic resection of prostate on the urinary function and complications after the surgery of prostatic hyperplasia. Methods:A total of 110 patients with prostatic hyperplasia admitted to Traditional Chinese Medical Hospital of Zhuji from July 2022 to December 2024 were selected and divided into the study group and the control group according to different treatment methods,with 55 cases in each group. The control group was treated with conventional transurethral plasmakinetic resection of prostate,and the study group was additionally treated with Qianlie Zhulong Decoction based on the treatment in the control group. The changes in urinary function indexes, levels of serum sex hormones [testosterone(T), luteinizing hormone(LH), and follicle-stimulating hormone(FSH)], levels of inflammatory factors [C-reactive protein (CRP) and interleukin-6 (IL-6)] before and after treatment, and the incidence of complications were compared between the two groups. Results: After treatment, the prostate volume and bladder residual urine volume in the two groups were decreased when compared with those before treatment(P<0.05),and the maximum urine flow in the two groups was increased when compared with that before treatment(P<0.05);the prostate volume and bladder residual urine volume in the study group were lower than those in the control group, and the maximum urine flow was greater than that in the control group(P<0.05). After treatment, the T levels in the two groups were up-regulated when compared with those before treatment(P<0.05),and the levels of LH and FSH were down-regulated when compared with those before treatment(P<0.05);the T level in the study group was higher than that in the control group(P<0.05), and the levels of LH and FSH were lower than those in the control group(P< 0.05). After treatment,the levels of CRP and IL-6 in the two groups were increased when compared with those before treatment(P<0.05),and the above two levels in the study group were lower than those in the control group(P<0.05). The incidence of complications was 7.27%(4/55)in the study group,and 23.64%(13/55)in the control group,there being significance in the difference(P<0.05). Conclusion: The combination of Qianlie Zhulong Decoction and transurethral plasmakinetic resection of prostate can improve the urinary function and levels of serum sex hormones of patients after surgery of prostatic hyperplasia, and reduce the levels of inflammatory factors and the incidence of complications.

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吴丹,斯红杰.前列逐癃汤联合经尿道前列腺等离子电切术对前列腺增生术后排尿功能及并发症的影响[J].新中医,2025,57(21):63-67

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  • 在线发布日期: 2025-11-11
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