八段锦干预肿瘤患者术后康复效果Meta 分析
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R734.2

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Meta-Analysis of Effect of Baduanjin Intervention on Postoperative Rehabilitation in Cancer Patients
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    摘要:

    目的:采用Meta分析系统性评价八段锦对肿瘤术后患者康复效果的影响。方法:检索中国知网(CNKI)、 万方、维普(VIP) 数据库、中国生物医学文献数据库(SinoMed)、PubMed、The Cochrane Library和Embase数 据库自建库至2024年11月发表的有关八段锦干预肿瘤术后患者的随机对照试验(RCT),提取纳入文献的基本 资料并采用Cochrane协作网推荐的偏倚风险评估工具(RoB 2) 评价其质量,根据推荐分级的评估、制定与评 价(GRADE)证据质量分级系统对结局指标进行等级评价,使用Stata 14.0软件进行Meta分析。结果:共纳入 19项RCT研究,1 514例患者。Meta分析结果显示,八段锦干预显著降低了肿瘤术后患者的疲乏[SMD=-1.15, 95%CI(-1.68,-0.62)]、焦虑[SMD=-1.46,95%CI(-1.87,-1.04)]和抑郁[SMD=-1.15,95%CI(-1.52,-0.78)] 评分,并显著提高了患者的生活质量生理功能[WMD=6.55,95%CI (2.21,10.88)],社会功能[WMD=8.95, 95%CI (3.99,13.90)],生理职能[WMD=13.97,95%CI (8.77,19.17)],精神健康[WMD=10.14,95%CI (7.18,13.09)],情感职能[WMD=11.13,95%CI (3.86,18.39)],躯体疼痛[WMD=7.95,95%CI (1.92, 13.98)],活力[WMD=10.00,95%CI(7.14,12.85)],总体健康[WMD=8.47,95%CI(3.48,13.47)]。亚组 分析显示,干预疗程是导致异质性的重要因素之一。各项结局指标的GRADE证据质量多为中等或低等。结论:八 段锦干预能够显著改善肿瘤术后患者身体和心理健康,增强其整体康复效果。

    Abstract:

    Abstract: Objective: To systematically evaluate the effect of Baduanjin on the rehabilitation of postoperative cancer patients by means of Meta-analysis. Methods: Randomized controlled trials(RCTs) regarding Baduanjin intervention for postoperative cancer patients published from the establishment of the databases to November 2024 were retrieved from CNKI,Wanfang,VIP,SinoMed,PubMed,The Cochrane Library and Embase. The basic data of the included literature was extracted, and its quality was evaluated using the Risk of Bias Assessment Tool(RoB 2) recommended by the Cochrane Collaboration. The outcome indicators were graded according to the Grading of Recommendations Assessment,Development and Evaluation(GRADE)system,and Meta-analysis was performed using Stata 14.0 software. Results: A total of 19 RCTs involving 1 514 patients were included. The results of Meta-analysis showed that Baduanjin intervention significantly reduced the scores of fatigue [SMD=-1.15,95%CI(-1.68,-0.62)], anxiety [SMD=-1.46,95%CI(-1.87,-1.04)] and depression [SMD=-1.15,95%CI(-1.52,-0.78)] in postoperative cancer patients, and significantly improved the physiological function [WMD=6.55,95%CI(2.21,10.88)], social function [WMD=8.95, 95%CI(3.99,13.90)], role-physical [WMD=13.97,95%CI(8.77,19.17)], mental health [WMD=10.14,95%CI(7.18,13.09)],role-emotional [WMD=11.13,95%CI(3.86,18.39)],bodily pain [WMD=7.95, 95%CI(1.92,13.98)], vitality [WMD=10.00,95%CI(7.14,12.85)] and general health [WMD=8.47,95%CI(3.48, 13.47)] of patients' quality of life. Subgroup analysis showed that intervention course was one of the important factors leading to heterogeneity. The GRADE grading of each outcome indicator included moderate and low levels. Conclusion: Baduanjin intervention can significantly improve the physical and mental health of postoperative cancer patients and enhance their overall rehabilitation effect.

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祁江晗,程成,李彬,王珏.八段锦干预肿瘤患者术后康复效果Meta 分析[J].新中医,2025,57(21):164-172

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