Abstract：Objective：To observe the clinical effect of mind-regulating and qi-soothing linked acupuncture in the treatment of post-stroke sensory disorders. Methods：A total of 66 patients with stroke and sensory disorders who were diagnosed and treated in the Department of Rehabilitation of Guangdong Provincial Hospital of Chinese Medicine from June 2024 to February 2025 were selected. They were divided into the control group and the treatment group by a random number table method， with 33 cases in each group. During the treatment， 2 cases were lost to follow-up and 1 case discontinued due to disease progression in the control group，resulting in a final inclusion of 30 cases；2 cases were lost to follow-up in the treatment group，resulting in a final inclusion of 31 cases. Both groups received basic treatment. The control group was additionally given conventional acupuncture，while the treatment group was additionally treated with mind-regulating and qi-soothing linked acupuncture. Both groups received treatment for two weeks. The sensory function [Revised Nottingham Sensory Assessment（reNSA）score]，numbness/pain score [Visual Analogue Scale（VAS）score]， activities of daily living [Modified Barthel Index（MBI）score]， quality of life [Stroke-Specific Quality of Life Scale （SS-QOL） score]， and incidence of adverse reactions were compared between the two groups. Results： After treatment，the reNSA scores in both groups were increased when compared with those before treatment（P＜0.05），and the reNSA score in the treatment group was higher than that in the control group（P＜0.05）. After treatment，the VAS scores in both groups were decreased when compared with those before treatment（P＜0.05），and the VAS score in the treatment group was lower than that in the control group（P＜0.05）. After treatment，the MBI scores in both groups were elevated when compared with those before treatment（P＜0.05），while there being no significant difference between the two groups（P＞0.05）. After treatment，the SS-QOL scores in both groups were increased when compared with those before treatment（P＜0.05）， and the SS-QOL score in the treatment group was higher than that in the control group（P＜0.05）. No adverse reactions such as allergy，needle phobia during acupuncture，or infection occurred in either group during the treatment. Conclusion： Mind-regulating and qi-soothing linked acupuncture can effectively improve the sensory function of patients with post-stroke sensory disorders， reduce the degree of limb pain or numbness，and enhance quality of life.