Abstract： Based on epidemiological investigations and literature review， this study identifies qi deficiency syndrome as the core manifestation of chronic obstructive pulmonary disease （COPD）， persisting throughout its progression. In clinical practice， a sequential treatment strategy of reinforcing healthy qi and eliminating pathogenic factors in traditional Chinese medicine（TCM）can be formulated according to the evolutionary characteristics of qi deficiency syndrome at different stages of COPD. During the acute exacerbation stage of COPD，the disease is mainly characterized by phlegm-heat syndrome and phlegm-damp syndrome，complicated with lung qi deficiency syndrome. In terms of treatment， it adheres to the principle of relieving excess while supplementing deficiency. While conducting treatment of clearing，resolving，diffusing and descending，Chinese herbs for supplementing lung and boosting qi are administered as appropriate to consolidate the body's foundation and cultivate the original qi. The risk window period of acute exacerbation is a key stage affecting the disease progression. It is mainly characterized by the syndrome of intermingled deficiency and excess，qi deficiency syndrome is often accompanied by phlegm-damp syndrome and blood stasis syndrome，and the disease location extends from the lung to the spleen and kidney. In treatment，the combination of tonifying deficiency and relieving excess should be adopted， and the use of deficiency-tonifying herbs should be appropriately increased. While boosting the lung， the spleen should be regulated and nourished（with a focus on boosting qi and strengthening the spleen）. During the stable stage, the disease is mainly characterized by deficiency syndrome. Depending on the initial pathogenic factors encountered and the patient's constitution, qi deficiency often transforms into qi and yin deficiency syndrome or qi and yang deficiency syndrome, frequently accompanied by phlegm dampness syndrome and blood stasis syndrome. Treatment should focus on supplementing deficiency while relieving excess, with supporting healthy qi as the root approach. The aim is to regulate the manifestations of deficiency of yin and yang in the lung, spleen, and kidney, emphasizing warming the kidney and boosting qi. Simultaneously, incorporate herbs to remove phlegm and promote blood circulation, carefully preventing recurrent acute exacerbations. Additionally，herbs for resolving phlegm and dissipating stasis should be combined to reduce the frequency of recurrent acute exacerbations and help patients quickly enter the stable stage. According to the different stages of COPD and the law of syndrome evolution， dynamic intervention throughout the entire course of COPD is of great significance for expanding the TCM prevention and treatment ideas for chronic respiratory diseases and improving the overall management level of chronic diseases.