210 例非结核分枝杆菌肺病中医证候与影像学表现的关联性研究
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R563

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丽水市科技计划项目(2022SJZC042)


Study on the Correlation Between Traditional Chinese Medicine Syndrome Types and Imaging Manifestations in 210 Cases of Nontuberculous Mycobacterial Pulmonary Disease
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    摘要:

    目的:分析非结核分枝杆菌肺病中医证候分型与胸部影像学特征的关联性,为中医辨证分型提供 影像学客观依据。方法:采用回顾性研究方法,纳入2018年1月—2023年12月浙江中医药大学附属丽水中医 院结核病科收治的210例非结核分枝杆菌肺病患者,通过中医四诊合参进行辨证分型,结合高分辨率CT评估 病灶分布及形态特征与中医证候的相关性。结果:中医证型分布显示肺阴亏虚型41例(19.5%)、阴虚火旺型 67例(31.9%)、气阴两虚型102例(48.6%)。影像学分析显示病灶分布广泛,最常见于两肺上叶,其中右肺下 叶以气阴两虚型为主(50.98%),同时气阴两虚型更容易累及≥3个肺叶(83.33%)。病灶形态显示气阴两虚型 可多见支气管扩张、钙化和胸膜增厚,而阴虚火旺型更常见空洞,差异有统计学意义(P<0.05)。结论:非结 核分枝杆菌肺病中医证候分型与影像学特征具有显著相关性,病灶分布最常见于两肺上叶,其中右肺下叶以气 阴两虚型为主,同时气阴两虚型更容易累及≥3个肺叶,病灶形态多见支气管扩张、钙化和胸膜增厚,空洞形 成可作为阴虚火旺型影像学辨识标志。

    Abstract:

    Abstract: Objective: To analyze the correlation between traditional Chinese medicine (TCM) syndrome types and chest imaging features in nontuberculous mycobacterial pulmonary disease, and to provide an objective imaging basis for TCM syndrome differentiation. Methods: A retrospective study was conducted on 210 patients with nontuberculous mycobacterial pulmonary disease admitted to the Department of Tuberculosis, Lishui TCM Hospital Affiliated to Zhejiang Chinese Medical University,from January 2018 to December 2023. Syndrome differentiation was performed based on the comprehensive analysis of four examinations, and the correlation between lesions distribution and morphological characteristics assessed by high-resolution CT and TCM syndromes was analyzed. Results: The distribution of TCM syndrome types was as follows:lung yin deficiency type (41 cases,19.5%),yin deficiency with fire hyperactivity type (67 cases,31.9%),and qi-yin deficiency type (102 cases,48.6%). Imaging analysis showed widespread lesion distribution,most commonly in both upper lobes. Lesions in the right lower lobe were predominantly of the qi-yin deficiency type (50.98%), and the qi-yin deficiency type was also more likely to involve ≥ 3 lung lobes( 83.33%). Regarding lesion morphology,the qi-yin deficiency type showed a higher prevalence of bronchiectasis, calcification, and pleural thickening, while cavities were more commonly associated with yin deficiency with fire hyperactivity type, with statistically significant differences (P<0.05). Conclusion: TCM syndrome types in nontuberculous mycobacterial pulmonary disease show significant correlations with imaging features. Lesions are most commonly distributed in both upper lobes,with the right lower lobe predominantly associated with the qi-yin deficiency type, which also more frequently involves ≥ 3 lung lobes and often presents with bronchiectasis, calcification, and pleural thickening. Cavity formation can serve as an imaging identification marker for yin deficiency with fire hyperactivity type.

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丰银平,罗水荣,张尊敬.210 例非结核分枝杆菌肺病中医证候与影像学表现的关联性研究[J].新中医,2026,58(1):54-58

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  • 在线发布日期: 2026-01-12
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