Abstract: Objective: To observe the clinical efficacy of thumbtack needle-embedding therapy combined with acupoint application with Biqiu Powder for pediatric allergic rhinitis (AR). Methods:A total of 84 children with AR admitted to Zhejiang Greentown Cardiovascular Hospital from January 2023 to January 2025 were selected and divided into the trial group and the control group using the random number table method,with 42 cases in each group. Finally, 40 cases in the trial group and 39 cases in the control group completed the study. The control group received oral administration of Loratadine Tablets, while the trial group received additional thumbtack needle-embedding therapy combined with acupoint application with Biqiu Powder based on the control group's treatment. Both groups were treated for four weeks. The following indicators were compared between the two groups:clinical efficacy,traditional Chinese medicine syndrome scores, nasal symptom scores [Total Nasal Symptom Score (TNSS) scale], nasal ventilation function [peak expiratory flow( PEF),diurnal variation rate of PEF],serum inflammatory factors [interleukin-6( IL-6), interleukin-10 (IL-10)], immune function [immunoglobulin E (IgE)], and the incidence of adverse reactions. Results: After four weeks of treatment, the total effective rate in the trial group was 95.00% (38/40), which was significantly higher than that of 76.92% (30/39) in the control group (P<0.05). After treatment,the primary symptom scores, the secondary symptom scores, and the total scores of traditional Chinese medicine syndromes decreased in both groups compared with those before treatment (P<0.05),and the scores in the trial group were lower than those in the control group( P<0.05). After treatment,the scores of nasal congestion,nasal itching,runny nose,and sneezing in the TNSS scale and the total scores decreased in both groups compared with those before treatment (P<0.05),and the scores in the trial group were lower than those in the control group (P<0.05). After treatment,IL-6 and IgE levels decreased in both groups compared with those before treatment,and the levels of IL-6 and IgE in the trial group were lower than those in the control group (P<0.05); IL-10 levels increased in both groups compared with those before treatment,and the IL-10 level in the trial group was higher than that in the control group (P<0.05). After treatment, PEF levels increased in both groups compared with those before treatment, and the PEF level in the trial group was higher than that in the control group (P<0.05);the diurnal variation rate of PEF decreased in both groups compared with those before treatment,and the diurnal variation rate of PEF in the trial group was lower than that in the control group (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion:Thumbtack needle-embedding therapy combined with acupoint application with Biqiu Powder shows significant efficacy in treating children with AR. It can effectively alleviate clinical symptoms,improve nasal ventilation function and immune function, reduce systemic inflammatory responses, and demonstrates higher medication safety.