揿针埋针疗法联合鼻鼽散穴位贴敷治疗小儿过敏性鼻炎临床研究
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R276.1

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杭州市医药卫生科技项目(B20241931)


Clinical Study on Thumbtack Needle-Embedding Therapy Combined with Acupoint Application with Biqiu Powder for Pediatric Allergic Rhinitis
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    摘要:

    目的:观察揿针埋针疗法联合鼻鼽散穴位贴敷治疗小儿过敏性鼻炎(AR) 的临床疗效。方法:选 择2023年1月—2025年1月浙江绿城心血管病医院收治的84例AR患儿,按随机数字表法分为试验组和对照组 各42例,最终试验组完成研究40例,对照组完成研究39例。对照组给予口服氯雷他定片治疗,试验组在对照 组基础上给予揿针埋针疗法联合鼻鼽散穴位贴敷治疗,2组均治疗4周。比较2组临床疗效、中医证候积分、 鼻症状评分[鼻症状总分(TNSS) 量表]、鼻通气功能[最大呼气流速(PEF)、PEF昼夜变异率]、血清炎症 因子[白细胞介素-6(IL-6)、白细胞介素-10(IL-10)]、免疫功能[免疫球蛋白E(IgE)] 及不良反应发 生率。结果:治疗4周后,试验组总有效率95.00% (38/40),高于对照组76.92% (30/39)(P<0.05)。治疗 后,2组中医证候主症评分、次症评分及总积分较治疗前降低(P<0.05),且试验组中医证候主症评分、次症 评分及总积分低于对照组(P<0.05)。治疗后,2组TNSS量表中鼻塞、鼻痒、流涕、喷嚏评分及总分较治疗前 降低(P<0.05),且试验组低于对照组(P<0.05)。治疗后,2组IL-6、IgE 水平较治疗前降低,且试验组 IL-6、IgE水平低于对照组(P<0.05);2组IL-10水平较治疗前升高,且试验组IL-10水平高于对照组(P< 0.05)。治疗后,2组PEF水平较治疗前升高,试验组PEF水平高于对照组(P<0.05);2组PEF昼夜变异率较 治疗前降低,试验组PEF 昼夜变异率低于对照组(P<0.05)。2 组不良反应发生率比较,差异无统计学意 义(P>0.05)。结论:揿针埋针疗法联合鼻鼽散穴位贴敷治疗AR患儿疗效显著,可有效减轻临床症状,改善 鼻通气功能及免疫功能,减轻机体炎症反应,安全性高。

    Abstract:

    Abstract: Objective: To observe the clinical efficacy of thumbtack needle-embedding therapy combined with acupoint application with Biqiu Powder for pediatric allergic rhinitis (AR). Methods:A total of 84 children with AR admitted to Zhejiang Greentown Cardiovascular Hospital from January 2023 to January 2025 were selected and divided into the trial group and the control group using the random number table method,with 42 cases in each group. Finally, 40 cases in the trial group and 39 cases in the control group completed the study. The control group received oral administration of Loratadine Tablets, while the trial group received additional thumbtack needle-embedding therapy combined with acupoint application with Biqiu Powder based on the control group's treatment. Both groups were treated for four weeks. The following indicators were compared between the two groups:clinical efficacy,traditional Chinese medicine syndrome scores, nasal symptom scores [Total Nasal Symptom Score (TNSS) scale], nasal ventilation function [peak expiratory flow( PEF),diurnal variation rate of PEF],serum inflammatory factors [interleukin-6( IL-6), interleukin-10 (IL-10)], immune function [immunoglobulin E (IgE)], and the incidence of adverse reactions. Results: After four weeks of treatment, the total effective rate in the trial group was 95.00% (38/40), which was significantly higher than that of 76.92% (30/39) in the control group (P<0.05). After treatment,the primary symptom scores, the secondary symptom scores, and the total scores of traditional Chinese medicine syndromes decreased in both groups compared with those before treatment (P<0.05),and the scores in the trial group were lower than those in the control group( P<0.05). After treatment,the scores of nasal congestion,nasal itching,runny nose,and sneezing in the TNSS scale and the total scores decreased in both groups compared with those before treatment (P<0.05),and the scores in the trial group were lower than those in the control group (P<0.05). After treatment,IL-6 and IgE levels decreased in both groups compared with those before treatment,and the levels of IL-6 and IgE in the trial group were lower than those in the control group (P<0.05); IL-10 levels increased in both groups compared with those before treatment,and the IL-10 level in the trial group was higher than that in the control group (P<0.05). After treatment, PEF levels increased in both groups compared with those before treatment, and the PEF level in the trial group was higher than that in the control group (P<0.05);the diurnal variation rate of PEF decreased in both groups compared with those before treatment,and the diurnal variation rate of PEF in the trial group was lower than that in the control group (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion:Thumbtack needle-embedding therapy combined with acupoint application with Biqiu Powder shows significant efficacy in treating children with AR. It can effectively alleviate clinical symptoms,improve nasal ventilation function and immune function, reduce systemic inflammatory responses, and demonstrates higher medication safety.

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宁剑,李蓓,田晓玲,陈琴,王钰玉,张炜.揿针埋针疗法联合鼻鼽散穴位贴敷治疗小儿过敏性鼻炎临床研究[J].新中医,2026,58(1):103-109

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  • 在线发布日期: 2026-01-12
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