中医“五步”干预策略联合耳穴揿针治疗痰湿型多囊卵巢综合征临床研究
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R248;R711.75

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武义县科技计划项目(202418-2)


Clinical Study on Traditional Chinese Medicine "Five-Step" Intervention Strategy Combined with Auricular Point Thumbtack Needling for Polycystic Ovary Syndrome of Phlegm-Dampness Type
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    摘要:

    目的:观察中医“五步”干预策略联合耳穴揿针治疗痰湿型多囊卵巢综合征(PCOS) 的临床疗 效。方法:选取2023年9月—2024年9月武义县中医院收治的痰湿型PCOS患者84例,根据随机数字表法分为 对照组和联合组各42例。2组均给予炔雌醇环丙孕酮片治疗,对照组加用耳穴揿针治疗,联合组加用中医“五 步”干预策略联合耳穴揿针进行治疗。比较2组体质量指数(BMI) 及腰臀比(WHR),脂糖代谢指标[甘油 三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FPG)、胰岛素抵抗指数(HOMA-IR)]、血清性激 素指标[睾酮(T)、黄体生成素(LH)、卵泡刺激素(FSH)、LH/FSH] 水平、中医证候评分、心理状态[广 泛性焦虑量表(GAD-7) ]、自我效能[自我效能感量表(GSES) ] 及生活质量[生存质量量 表(MPCOSQ)]。结果:治疗后,2组BMI、WHR均较治疗前降低(P<0.05),且联合组BMI、WHR低于对 照组(P<0.05)。治疗后,2组TG、LDL-C、FPG、HOMA-IR水平均较治疗前降低(P<0.05),且联合组4项 代谢指标水平均低于对照组(P<0.05)。治疗后,2组T、LH、FSH、LH/FSH均较治疗前降低(P<0.05),且 联合组4 项性激素水平均低于对照组(P<0.05)。治疗后,2 组中医证候评分、GAD-7 评分均较治疗前降 低(P<0.05),且联合组2项评分均低于对照组(P<0.05)。治疗后,2组GSES评分、MPCOSQ评分均较治疗 前升高(P<0.05),且联合组2项评分均高于对照组(P<0.05)。结论:中医“五步”干预策略联合耳穴揿针 可以减轻痰湿型PCOS患者肥伴体征,改善内分泌功能,调节患者心理状态,提高生活质量。

    Abstract:

    Abstract:Objective:To observe the clinical efficacy of the traditional Chinese medicine "five-step" intervention strategy combined with auricular point thumbtack needling in treating polycystic ovary syndrome (PCOS) of phlegm- dampness type. Methods: A total of 84 PCOS patients of phlegm-dampness type treated at Wuyi County Hospital of Traditional Chinese Medicine from September 2023 to September 2024 were selected and randomly divided into the control group and the combination group using the random number table method, with 42 cases in each group. Both groups were treated with Ethinylestradiol and Cyproterone Acetate Tablets. The control group additionally received auricular point thumbtack needling, while the combination group received a traditional Chinese medicine "five-step" intervention strategy combined with auricular point thumbtack needling. Comparisons were made between the two groups regarding body mass index( BMI),waist-to-hip ratio( WHR),lipid and glucose metabolism indicators [triglycerides( TG), low-density lipoprotein cholesterol (LDL-C), fasting plasma glucose (FPG), Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)],serum sex hormone levels [testosterone (T),luteinizing hormone (LH),folliclestimulating hormone (FSH), LH/FSH ratio], traditional Chinese medicine syndrome scores, psychological status [Generalized Anxiety Disorder Scale (GAD-7)], self-efficacy [General Self-Efficacy Scale (GSES)], and quality of life [Modified Polycystic Ovary Syndrome Quality of Life Questionnaire (MPCOSQ)]. Results:After treatment,BMI and WHR decreased in both groups compared to before treatment (P<0.05), with lower values in the combination group (P<0.05). TG, LDL-C, FPG, and HOMA-IR levels decreased in both groups compared to before treatment (P<0.05), with lower levels in the combination group (P<0.05). T, LH, FSH, and LH/FSH ratio decreased in both groups compared to before treatment (P<0.05), with lower levels in the combination group (P< 0.05). Traditional Chinese medicine syndrome scores and GAD-7 scores decreased in both groups compared to before treatment (P<0.05),with lower scores in the combination group (P<0.05). GSES and MPCOSQ scores increased in both groups compared to before treatment (P<0.05), with higher scores in the combination group (P<0.05). Conclusion: The traditional Chinese medicine "five-step" intervention strategy combined with auricular point thumbtack needling can reduce obesity-related signs,improve endocrine function,regulate psychological status,and enhance quality of life in PCOS patients of phlegm-dampness type.

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陈琪如,刘震,邵巧燕,钟杭欣.中医“五步”干预策略联合耳穴揿针治疗痰湿型多囊卵巢综合征临床研究[J].新中医,2026,58(2):92-97

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  • 在线发布日期: 2026-01-29
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