Abstract：Objective：To observe the clinical efficacy of Yinjia Wan plus Shixiao San combined with western medicine in treating pelvic inflammatory disease （PID） of damp-heat and blood stasis stagnation type. Methods： A total of 128 patients with PID of damp-heat and blood stasis stagnation type treated in the Department of Gynecology and Obstetrics，Wenling Hospital of Traditional Chinese Medicine between January and April 2025 were enrolled and randomly assigned to either a trial group or a control group （64 cases each） using a random number table method. Both groups received conventional antibiotic therapy，while the trial group additionally received Yinjia Wan plus Shixiao San. Treatment duration was one month for both groups. Traditional Chinese medicine （TCM） syndrome scores，Visual Analogue Scale （VAS） scores for pelvic pain，uterine artery blood flow parameters [peak systolic velocity （PSV）， resistance index （RI）， pulsatility index （PI）]， and inflammatory cytokine levels [tumor necrosis factor-α （TNF-α），interleukin （IL） -2，IL-6，IL-10] were assessed before and after treatment. Clinical efficacy and incidence of adverse reactions were also compared. Results：After treatment，the total effective rate in the trial group was 91.94% （57/62）， significantly higher than that of 74.19% （46/62） in the control group （P＜ 0.05）. TCM syndrome scores and pelvic pain VAS scores in both group were decreased compared with those before treatment （P＜0.05），and the two scrores in the trial group were lower than those in the control group （P＜0.05）. Uterine artery PSV in both groups were increased compared with those before treatment， while RI and PI were decreased in both groups compared with those before treatment，the differences being significant （P＜0.05）. Uterine artery PSV in the trial group was faster than that in the control group，uterine artery RI and PI in the trial group were lower than those in the control group，the differences being significant （P＜0.05）. Levels of IL-6 and TNF-α were decreased， while IL-2 and IL-10 were increased in both groups compared with those before treatment， the differences being significant（P＜0.05）. Levels of IL-6 and TNF-α were lower than those in the control group，levels of IL-2 and IL-10 were higher than those in the control group， the differences being significant （P＜0.05）. The incidence of adverse reactions during the study period showed no significant difference between the two groups （P＞ 0.05）. Conclusion： Yinjia Wan plus Shixiao San combined with western medicine exerts better efficacy than western medicine alone in treating PID of damp-heat and blood stasis stagnation type， with more significant pain relief，symptom alleviation，uterine artery blood circulation improvement and inflammatory response reduction，and favorable safety.