200例慢性阻塞性肺疾病前期人群基本特征与中医体质分布横断面研究
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R256.1;R563

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国家自然科学基金面上项目(82474407);中华中医药学会青年求实项目(2022-QNQSDEP-04);中医证候全国重点实验室揭榜挂帅项目(SKLKY2025C0005);广东省名中医传承工作室建设项目(粤中医办函〔2023〕108号);广东省中医院中医药科学技术研究专项(YN2023MS02)


Cross-Sectional Study on Basic Characteristics and Traditional Chinese Medicine Constitution Distribution in 200 Pre-Chronic Obstructive Pulmonary Disease Cases
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    摘要:

    目的:分析慢性阻塞性肺疾病前期(pre-COPD) 人群的基本特征与中医体质分布情况,为pre- COPD识别和中西医结合防治提供循证医学依据。方法:采用横断面研究方法,收集2024年7月—2025年1月 在广东省中医院、广州善心健康医疗中心、东莞市中西医结合医院和东莞市横沥镇社区卫生服务中心诊疗的 pre-COPD人群的一般资料、慢性阻塞性肺疾病(COPD) 危险因素、呼吸道症状、中医四诊信息、中医体质等 数据,采用描述性统计、二元Logistic回归分析人群的基本特征及中医体质分布规律。结果:共调查了200例 pre-COPD人群,分析发现以小气道功能障碍(SAD) 亚型居多(103例,51.50%),其次为保留比值受损肺功 能(PRISm) 合并SAD人群(31例,15.50%),慢性支气管炎(CB) 合并SAD人群(18例,9.00%);主要呼吸 道症状为咳嗽(94例,47.00%)、咳痰(88例,44.00%);职业暴露史及吸烟史为pre-COPD人群出现呼吸道症 状的危险因素(P<0.05);常见的中医四诊信息包括偶有咳嗽(82例,41.00%)、气短(75例,37.50%)、腻 苔(144 例,72.00%)、白苔(137 例,68.50%) 和细脉(53 例,26.50%);中医体质方面,以偏颇体质多 见(126例,63.00%),其中以阳虚质人群居多(57例,28.50%)。结论:pre-COPD人群以SAD亚型多见,大 部分人群存在呼吸道症状,主要为咳嗽、咳痰,具有吸烟史及职业暴露史为出现呼吸道症状的危险因素;常见 舌象为腻苔、白苔;常见脉象为细脉;中医偏颇体质以阳虚质多见。

    Abstract:

    Abstract:Objective:To analyze the basic characteristics and traditional Chinese medicine (TCM) constitution distribution in a pre-chronic obstructive pulmonary disease (pre-COPD) population, and to provide evidence-based medical basis for the identification and integrated traditional Chinese and western medicine prevention and treatment of pre-COPD. Methods: Using a cross-sectional study design, data were collected from pre-COPD individuals diagnosed between July 2024 and January 2025 at Guangdong Provincial Hospital of Chinese Medicine, Guangzhou Kindness Health Care Medical Center, Dongguan Hospital of Integrated Traditional Chinese and Western Medicine, and Dongguan Hengli Community Health Service Center. The collected data included general information,COPD risk factors, respiratory symptoms, TCM four diagnostic information, and TCM constitutions. Descriptive statistical analysis and binary Logistic regression were used to analyze the basic characteristics and TCM constitution distribution patterns of the population. Results: A total of 200 pre-COPD individuals were surveyed. Analysis revealed that the small airway dysfunction (SAD) subtype was the most common (103 cases,51.50%),followed by the preserved ratio impaired spirometry (PRISm) combined with SAD group (31 cases, 15.50%), and the chronic bronchitis (CB) complicated with SAD group (18 cases,9.00%). The main respiratory symptoms were cough (94 cases,47.00%) and expectoration( 88 cases,44.00%). Occupational exposure history and smoking history were risk factors for the presence of respiratory symptoms in the pre-COPD population (P<0.05). Common TCM four diagnostic information included occasional cough (82 cases, 41.00%), shortness of breath (75 cases, 37.50%), greasy coating (144 cases, 72.00%),white coating( 137 cases,68.50%),and thready pulse( 53 cases,26.50%). Regarding TCM constitutions, biased constitutions were common (126 cases, 63.00%), with yang deficiency constitution being the most common (57 cases,28.50%). Conclusion:The distribution of pre-COPD population is predominantly characterized by the SAD subtype, with most individuals exhibiting respiratory symptoms, primarily cough and expectoration. Smoking history and occupational exposure history are risk factors for developing respiratory symptoms. Common tongue manifestations are greasy coating and white coating;a common pulse condition is the thready pulse. Among TCM biased constitutions,yang deficiency constitution is the most common.

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朱方刚,林泺琪,肖晶旻,陈远彬,林琳,吴蕾.200例慢性阻塞性肺疾病前期人群基本特征与中医体质分布横断面研究[J].新中医,2026,58(4):8-14

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  • 在线发布日期: 2026-02-22
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