Abstract： By analyzing the chapters related to gynecological diseases in WANG Zhizhong's work Zhen Jiu Zi Sheng Jing （Classic of Nourishing Life with Acupuncture and Moxibustion）， this study summarizes his principles of acupoint selection. It is concluded that WANG Zhizhong emphasized choosing acupoints from the conception vessel （CV） and the foot-taiyin kidney channel when treating gynecological diseases with acupuncture and moxibustion. He strengthened meridian connections and promoted the smooth flow of qi and blood through intersecting acupoints and the five transport points. Additionally， WANG Zhizhong focused on standardizing acupuncture and moxibustion treatments and combined moxibustion with herbal medicine，forming distinctive therapeutic features. For gynecological conditions such as menstrual disorders， red vaginal discharge， infertility， and persistent lochia， he addressed the complex pathogenesis of interweaved deficiency and excess syndrome，emphasized reinforcing deficiency and reducing excess，and skillfully combined disease and syndrome with acupoint selection，developing personalized diagnostic and therapeutic characteristics. This approach provides valuable insights for the traditional Chinese medicine treatment of gynecological diseases.