Abstract： Objective： To observe the clinical efficacy of Banxia Baizhu Tianma Decoction combined with the eight-section brocade in rehabilitation exercise in the treatment of hypertension. Methods：A total of 188 patients with hypertension admitted to Huzhou Wuxing Hospital of Traditional Chinese and Western Medicine from January 2024 to January 2025 were selected and divided into group A， group B， group C， and the control group using the random number table method， with 47 patients in each group. All patients received conventional antihypertensive treatment. Group A underwent the eight-section brocade in rehabilitation exercise， group B received Banxia Baizhu Tianma Decoction，and group C received the combination of Banxia Baizhu Tianma Decoction and the eight-section brocade in rehabilitation exercise. The control group received only conventional antihypertensive treatment. The treatment lasted for three months continuously. Blood pressure， inflammatory factors [C-reactive protein （CRP）， homocysteine （HCY）， interleukin-6 （IL-6）] and serum ficolin-3 levels were compared among the four groups，and the incidence of adverse reactions was recorded. Results：The total effective rate in group C was higher than that in the other three groups （P＜ 0.05），and the rates in group A and group B were higher than that in the control group （P＜0.05）. After three months of treatment，diastolic and systolic blood pressure decreased in all four groups compared to before treatment （P＜0.05）. Diastolic and systolic blood pressure in group C were lower than those in the control group，group A，and group B（ P＜ 0.05）. Diastolic and systolic blood pressure in group A and group B were lower than those in the control group （P＜ 0.05）. After three months of treatment，levels of CRP，HCY，and IL-6 decreased，and ficolin-3 levels increased in all four groups compared to before treatment （P＜0.05）. Group C had lower levels of CRP，HCY，and IL-6 and higher levels of ficolin-3 compared to the control group，group A，and group B （P＜0.05）. Group A and group B had lower levels of CRP，HCY，and IL-6 and higher levels of ficolin-3 compared to the control group （P＜0.05）. There was no statistically significant difference in the incidence of adverse reactions among the four groups （P＞0.05）. Conclusion： The combination of Banxia Baizhu Tianma Decoction and the eight-section brocade in rehabilitation exercise can improve the clinical efficacy， reduce blood pressure， ameliorate inflammatory response， and shows good safety in patients with hypertension.