疏风止痛饮联合小针刀治疗老年神经根型颈椎病临床研究
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R246.9

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2023年度河南省中医药科学研究专项课题(2023ZY2127)


Clinical Study on Shufeng Zhitong Decoction Combined with Small Acupotomy for Senile Cervical Spondylotic Radiculopathy
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    摘要:

    目的:观察疏风止痛饮联合小针刀治疗老年神经根型颈椎病(CSR) 的疗效。方法:选取2023年 3月—2024年3月漯河市中心医院收治的112例老年CSR患者,按随机数字表法分为对照组及研究组各56例。 对照组采用小针刀治疗,研究组采用疏风止痛饮联合小针刀治疗。比较2组临床疗效及不良反应发生率,比较 2组治疗前后中医证候积分、椎动脉血流动力学[收缩期峰流速(Vs)、舒张末期峰流速(Vd)]、疼痛程度 [视觉模拟评分法(VAS)]、颈椎功能[颈椎功能障碍指数(NDI)]、颈部肌力、血清炎性因子水平[C-反 应蛋白(CRP)、肿瘤坏死因子-α (TNF-α)、白细胞介素-1β (IL-1β)、白细胞介素-6 (IL-6)] 的变化。 结果:研究组临床疗效总有效率为96.43% (54/56),对照组为82.14% (46/56),2组比较,差异有统计学意 义(P<0.05)。治疗后,2组眩晕、头痛、肢体瘫痹、肢体麻木中医证候积分均较治疗前下降(P<0.05),研 究组上述4项中医证候积分均低于对照组(P<0.05)。治疗后,2组椎动脉Vs、椎动脉Vd指标值均较治疗前升 高(P<0.05),VAS、NDI评分均较治疗前下降(P<0.05);研究组椎动脉Vs、椎动脉Vd指标值均高于对照 组(P<0.05),VAS、NDI评分均低于对照组(P<0.05)。治疗后,2组后颈部右侧屈、左侧屈、后伸、前屈肌 力均较治疗前提升(P<0.05),研究组后颈部右侧屈、左侧屈、后伸、前屈肌力均高于对照组(P<0.05)。治 疗后,2组血清CRP、TNF-α、IL-1β、IL-6水平均较治疗前下降(P<0.05),研究组血清CRP、TNF-α、IL-1β、 IL-6水平均低于对照组(P<0.05)。研究组不良反应发生率为5.36%(3/56),对照组为1.79%(1/56),2组不 良反应发生率比较,差异无统计学意义(P>0.05)。结论:疏风止痛饮联合小针刀治疗老年CSR疗效确切,可 改善临床症状,增加椎动脉血流量,减轻疼痛程度,改善颈椎功能、颈部肌力,抑制炎性反应,安全性高。

    Abstract:

    Abstract: Objective: To observe the efficacy of Shufeng Zhitong Decoction combined with small acupotomy in the treatment of senile cervical spondylotic radiculopathy (CSR). Methods: A total of 112 elderly CSR patients admitted to Luhe Central Hospital from March 2023 to March 2024 were selected and divided into the control group and the study group using the random number table method,with 56 cases in each group. The control group received small acupotomy therapy,while the study group received Shufeng Zhitong Decoction combined with small acupotomy therapy. The clinical efficacy and incidence of adverse reactions were compared between the two groups. Comparisons were also made regarding changes in traditional Chinese medicine syndrome scores,vertebral artery hemodynamics [systolic peak velocity( Vs),end-diastolic peak velocity( Vd)],pain degree [Visual Analogue Scale( VAS)],cervical function [Neck Disability Index (NDI)], neck muscle strength, and serum inflammatory factor levels [C-reactive protein (CRP), tumor necrosis factor- α (TNF- α), interleukin-1β (IL-1β), interleukin-6 (IL-6)] before and after treatment. Results:The total clinical effective rate was 96.43% (54/56) in the study group and 82.14% (46/56) in the control group,with a statistically significant difference between the two groups (P<0.05). After treatment,traditional Chinese medicine syndrome scores for dizziness, headache, limb weakness and paralysis, and limb numbness decreased in both groups compared to before treatment (P<0.05),and the scores for these four items in the study group were lower than those in the control group (P<0.05). After treatment,vertebral artery Vs and Vd values increased in both groups compared to before treatment (P<0.05), while VAS and NDI scores decreased (P<0.05). The study group showed higher vertebral artery Vs and Vd values than the control group (P<0.05),and lower VAS and NDI scores (P<0.05). After treatment, muscle strength for right lateral flexion, left lateral flexion, extension, and flexion of the posterior neck improved in both groups compared to before treatment (P<0.05),and the study group's muscle strength for these movements was greater than that of the control group (P<0.05). After treatment, serum levels of CRP, TNF-α, IL-1β, and IL-6 decreased in both groups compared to before treatment (P<0.05), and serum levels of CRP, TNF-α,IL-1β,and IL-6 in the study group were lower than those in the control group (P<0.05). The incidence of adverse reactions was 5.36% (3/56) in the study group and 1.79% (1/56) in the control group, with no statistically significant difference between the two groups (P>0.05). Conclusion:Shufeng Zhitong Decoction combined with small acupotomy is effective in the treatment of elderly CSR. It can improve clinical symptoms,increase vertebral artery blood flow,reduce pain,improve cervical function and neck muscle strength,inhibit inflammatory responses,and exhibits high safety.

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刘亚东,汪庆玎,郭健,水根会.疏风止痛饮联合小针刀治疗老年神经根型颈椎病临床研究[J].新中医,2026,58(5):49-54

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  • 在线发布日期: 2026-03-12
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