Abstract：Objective：To observe the effect of tuina combined with the six-character formula on rehabilitation in elderly patients with coronary heart disease （CHD） after percutaneous coronary intervention （PCI）. Methods：A total of 102 elderly CHD patients who underwent PCI and were admitted to Zhejiang Integrated Traditional Chinese and Western Medicine Hospital from January 2020 to January 2025 were selected. They were divided into the control group （n=48） and the observation group （n=54） according to different nursing schemes. The control group received conventional rehabilitation nursing，while the observation group received additional treatment with tuina combined with the six-character formula on the basis of the control group's regimen. Changes in lung function indices [forced vital capacity （FVC）， forced expiratory volume in the first second （FEV1）， maximum voluntary ventilation （MVV）]， exercise tolerance indices， ventilatory function indices， sleep quality scores， anxiety scores， and depression scores before and after the intervention were compared between the two groups. The incidence of major adverse cardiovascular events was also compared. Results： After intervention， FVC， FEV1， and MVV levels increased in both groups compared to before intervention （P＜0.05），and the levels of these three indices were higher in the observation group than in the control group （P＜0.05）. After intervention，peak oxygen uptake，peak oxygen uptake per kilogram，and peak metabolic equivalent levels increased in both groups compared to before intervention （P＜0.05），and the levels of these three indices were higher in the observation group than in the control group （P＜0.05）. After intervention，peak oxygen pulse and peak ventilation levels increased in both groups compared to before intervention （P＜0.05），while the slope of the ventilatory equivalent for carbon dioxide decreased （P＜0.05）. The levels of peak oxygen pulse and peak ventilation in the observation group were higher than those in the control group （P＜0.05）， and the slope of the ventilatory equivalent for carbon dioxide in the observation group was lower than that in the control group （P＜0.05）. After intervention， scores of sleep quality， anxiety， and depression decreased in both groups compared to before intervention （P＜0.05）， and these three scores were lower in the observation group than in the control group （P＜ 0.05）. The total incidence of major adverse cardiovascular events was 3.70% （2/54） in the observation group and 8.33% （4/48） in the control group， with no statistically significant difference between the two groups （P＞0.05）. Conclusion： Tuina combined with the six-character formula can improve cardiopulmonary function， exercise tolerance，and psychological state in elderly CHD patients after PCI，with a high safety profile.