Abstract： Objective： To observe the clinical efficacy of acupoint pressure stimulation patches combined with atomization in the treatment of mycoplasma pneumoniae pneumonia in children. Methods：A retrospective analysis was conducted on 100 children with mycoplasma pneumoniae pneumonia treated at Taizhou Central Hospital from March 2023 to February 2025. They were divided into two groups based on treatment methods：the control group （58 cases） and the acupoint patch group （42 cases）. Both groups received Azithromycin for anti-infective treatment and corresponding symptomatic treatment. The control group received conventional atomization therapy，while the acupoint patch group received acupoint pressure stimulation patches on the basis of the treatment of the control group. The clinical efficacy，the time to improvement of cough and wheezing，and the changes in traditional Chinese medicine syndrome scores before and after treatment were compared between the two groups. Results： The total effective rate of clinical efficacy was 84.48% （49/58） in the control group and 97.62% （41/42） in the acupoint patch group， the difference being significant （P＜0.05）. The time to improvement of cough，lung rales，and wheezing in the acupoint patch group was earlier than that in the control group （P＜0.05）. After treatment，the traditional Chinese medicine syndrome scores for cough severity，wheezing，fever，and expectoration in both groups decreased compared to before treatment （P＜ 0.05）. The traditional Chinese medicine syndrome scores for cough severity and wheezing in the acupoint patch group were lower than those in the control group （P＜0.05）；there was no statistically significant difference in the traditional Chinese medicine syndrome scores for fever and expectoration between the two groups（ P＞0.05）. Conclusion：Acupoint pressure stimulation patches combined with atomization show good efficacy in the treatment of mycoplasma pneumoniae pneumonia in children. This combination can quickly alleviate clinical symptoms such as cough and wheezing， accelerate recovery，and can serve as an adjunctive therapy for mycoplasma pneumoniae pneumonia.