Abstract：Objective：To observe the clinical efficacy of acupoint injection combined with small acupotomy and Chinese medicine package therapy in addition to western medication for frozen shoulder with cold-damp blockage syndrome. Methods： A total of 75 patients with frozen shoulder of cold-damp blockage syndrome who visited the Orthopedics and Traumatology Outpatient Clinic of Yongjia Hospital of Traditional Chinese Medicine from May 2023 to September 2024 were selected. They were divided into the control group（ 38 cases） and the observation group（ 37 cases） using the simple randomization method. During the study，a total of nine cases were excluded or dropped out （five from the control group， four from the observation group）， resulting in 33 cases completing the study in each group. The control group was treated with oral Celecoxib Capsules combined with Eperisone Hydrochloride Tablets. The observation group received the same western medication as the control group，with the addition of acupoint injection combined with small acupotomy and Chinese medicine package therapy. Clinical efficacy， traditional Chinese medicine syndrome scores，shoulder pain severity [Visual Analogue Scale （VAS） scores]，and Constant-Murley shoulder function scores before and after treatment were compared between the two groups. Results： After one month of treatment， the total effective rate in the observation group was 96.97% （32/33）， higher than that of 78.79% （26/33） in the control group （P＜0.05）. The scores for wandering shoulder pain，aversion to wind and cold，pain aggravated by exposure to wind and cold， and shoulder heaviness were decreased in both groups compared to before treatment （P＜0.05）. The observation group had lower scores for these traditional Chinese medicine syndrome items than the control group （P＜ 0.05）. The VAS scores decreased in both groups compared to before treatment （P＜0.05），and the observation group had a lower VAS score than the control group （P＜0.05）. The scores for shoulder pain，activities of daily living，range of motion， muscle strength， and the total Constant-Murley score increased in both groups compared to before treatment （P＜0.05）. The observation group had higher scores for these Constant-Murley items and the total score than the control group （P＜0.05）. Conclusion： Application of acupoint injection combined with small acupotomy and Chinese medicine package therapy in addition to western medication can further alleviate pain and improve shoulder joint function in patients with frozen shoulder of cold-damp blockage syndrome.