Abstract： This article introduces Professor XIONG Guoliang's clinical experience in treating diabetic kidney disease using the method of tonification and consolidation. Professor XIONG believes that the root cause of diabetic kidney disease lies in spleen and kidney qi deficiency， with the core pathogenesis being deficiency of healthy qi and leakage of essential substances. The treatment should focus on supplementing qi， strengthening the spleen， and consolidating the kidney to astringe essence. The clinical approach encompasses three key principles： "tonifying the spleen and kidney" as the foundation of treatment，"consolidating to astringe essence" as the crucial step to halt disease progression， and "resolving stasis and promoting diuresis" as the pivotal measure to clear obstacles. A customized formula，Xiaoke Shen'an Decoction，is formulated and modified according to the syndrome manifestation.