Abstract： This article is to introduce Professor WEI Aisheng's clinical experience in treating type 2 diabetes mellitus. Professor WEI believes that "spleen deficiency，flesh injury，and failure of six stagnations in dispersion" is the key pathogenesis of type 2 diabetes mellitus. Based on this，he summarizes the following diagnostic points：first， differentiate whether the pathogenesis is deficiency or excess； second， differentiate the types of flesh injury； third， determine the key points of syndrome differentiation of the free flow of water and food passages. Among these， "flesh injury" can be classified into three syndromes： flesh deficiency， flesh excess， and flesh stiffness. The treatment methods include strengthening the flesh， reducing the flesh， and activating the flesh. Commonly used therapeutic principles are strengthening the spleen and promoting its function， as well as resolving the six stagnations. The experience-based prescription Liuhe Decoction is selected and modified according to symptoms. Simultaneously， he emphasizes guiding patients in dietary therapy and exercise，thus achieving satisfactory efficacy.