Abstract：This paper introduces MENG Xiangxin's clinical experience in treating diabetic nephropathy based on the theory of deficiency， stasis， and toxin. Professor MENG Xiangxin considers dampness， stasis， toxin， and deficiency as the core pathological elements of diabetic nephropathy， and has established a three-stage syndrome differentiation and treatment model of deficiency-stasis-toxin. This system integrates the early stage， clinical stage， and renal failure stage of diabetic nephropathy with the dynamic evolution of traditional Chinese medicine syndromes. In terms of treatment， she emphasizes stage-based therapeutic principles， combining syndrome differentiation with symptom management， and integrating acupuncture with medicine.This approach forms a distinctive diagnostic and therapeutic framework and achieves certain clinical efficacy.