Abstract： Syndrome differentiation of the hands and feet is an important component of the Chinese medicine diagnostic system. Among these，warm hands and feet is a common symptom of the extremities in clinical practice. It can reflect the yin-yang and cold-heat balance of the body，the function of the spleen and stomach，and the prognosis of the disease， thus possessing significant diagnostic value. Using the framework of six-meridian syndrome differentiation，this article systematically reviews the articles and formula-syndrome patterns related to warm hands and feet in the Shang Han Za Bing Lun （Treatise on Cold Damage and Miscellaneous Diseases），analyzes the pathogenesis of warm hands and feet，and summarizes the characteristics of formulas in the treatment of warm hands and feet such as Guizhi Decoction， Zhizi Chi Decoction， Zhizi Dahuang Decoction， Sanwu Huangqin Decoction， Xiaochaihu Decoction， Xiaojianzhong Decoction， Xiaoshi Fanshi Powder， and Wenjing Decoction. Furthermore， based on the pathogenesis and the discussions and treatment experiences of later physicians， this article also explores the formula and medication approaches for patterns with documented pathogenesis but no specific formula， such as "the disease location is in the spleen-taiyin meridian， which pertains to the interior syndrome" and "heat has entered the blood aspect and attributed to the bladder，" aiming to provide a reference for precise clinical differentiation and treatment.