Abstract： This paper introduces Professor LAO Jinxiong′s clinical experience in treating post-stroke mental disorders with acupuncture and moxibustion using the primordial qi-cultivating and heart-nourishing method. Professor LAO Jinxiong holds that the pathogenesis of post-stroke mental disorders is fundamentally rooted in the deficiency of essence and primordial qi as well as insufficiency of marrow sea，with disordered qi movement and internal generation of phlegm and stasis as the pivotal mechanism， and malnourishment of the heart spirit and failure of governance by the primordial spirit as the core. The treatment is guided by the principles of replenishing essence and cultivating the primordial qi，regulating and unblocking qi movement，and calming the spirit and nourishing the heart，with stagespecific treatment according to the early， middle， and late stages. In clinical practice， Professor LAO Jinxiong has developed a four-step diagnostic and therapeutic approach encompassing pulse palpation，inspection，tendon soothing， and palpatory examination. He selects the five back-shu points to perform the heat-producing needling technique and warm needling moxibustion to cultivate the primordial qi and consolidate the foundation， combines Hegu （LI4） and Taichong （LR3） points to open the four gates for regulating qi and unblocking the collaterals，applies the directional reducing method at Neiguan （PC6） points to protect the heart and open the orifices， and administers corresponding stimulation according to the specific damage of the primordial spirit and the conscious spirit. This paper presents Professor LAO Jinxiong′s clinical experience of emphasizing moxibustion to cultivate the primordial qi， regulating qi based on syndrome differentiation，and nourishing the heart in a stage-specific manner.