Abstract： Objective： To summarize the medication rules of Professor FAN Yongsheng in treating connective tissue disease-related cardio disorders based on the Traditional Chinese Medicine Inheritance Support System（ TCMISS）. Methods： Prescription data of patients with connective tissue diseases treated by Professor FAN Yongsheng were collected， from which 200 prescriptions associated with cardiac disorders were screened. Following standardized data processing， a medical record cohort was established using the TCMISS， where four diagnostic information， prescription data，and traditional Chinese and western medicine diagnostic data were imported. The built-in analytical modules of the platform were utilized to establish herb-herb and symptom-herb association networks. By analyzing the driver herbs frequently prescribed in Professor FAN′s clinical practice， this study aimed to explore his medication characteristics and compatibility rules. Results： In Professor FAN′s treatment of connective tissue disease-related cardiac disorders， symptoms with a frequency of ≥ 30 times included insomnia， palpitations， dizziness， chest tightness，and chest pain. Among the 200 prescriptions，a total of 176 Chinese herbal medicines were used， among which 55 herbs with a frequency of ≥20 times and 23 herbs with a frequency of ≥40 times. The top 10 herbs in terms of frequency were Poria， Artemisiae Annuae Herba， stir-fried Paeoniae Radix Alba， stir-fried Atractylodis Macrocephalae Rhizoma， raw Glycyrrhizae Radix et Rhizoma， Citri Sarcodactylis Fructus， Glycyrrhizae Radix et Rhizoma Praeparata cum Melle， Pinelliae Rhizoma Praeparatum cum Zingibere et Alumine， Astragali Radix， and Coicis Semen. Using the PageRank algorithm，25 driver herbs were identified. The four natures of the high-frequency herbs were mainly neutral， cold， and warm； the five flavors were mainly sweet， bitter， and pungent； and the meridian tropisms were mainly the spleen， liver， lung， stomach， and heart meridians. Commonly used herb pairs included： Allii Macrostemonis Bulbus-Trichosanthis Pericarpium； Glycyrrhizae Radix et Rhizoma Praeparata cum Melle-stir-fried Paeoniae Radix Alba，Chuanxiong Rhizoma，and Cinnamomi Ramulus；Moutan Cortex-Rehmanniae Radix； and Cinnamomi Ramulus-Chuanxiong Rhizoma， among others. Symptom-herb associations included： qi obstruction of chest-Pinelliae Rhizoma Praeparatum cum Zingibere et Alumine and Allii Macrostemonis Bulbus； vertigo-Atractylodis Macrocephalae Rhizoma and Gastrodiae Rhizoma； palpitations-Glycyrrhizae Radix et Rhizoma Praeparata cum Melle and Cinnamomi Ramulus； insomnia-Caulis Polygoni Multiflori and Ziziphi Spinosae Semen， among others. Conclusion： Professor FAN Yongsheng′s treatment of connective tissue disease-related cardiac disorders is primarily based on clearing heat and eliminating toxicity， with flexible modifications incorporating herbs that tonify deficiency，regulate qi，resolve phlegm，promote diuresis，and invigorate blood circulation.